Simon Nadal 

Chercheur

Junior Group Leader


CDD, Chimie Biologique

Site de Cergy

https://orcid.org/0000-0002-0748-0284

Chemical biology

Proteomics

Protein chemistry

Multiple Myeloma


8 documents


Articles dans une revue

  • Lorenzo Meneghelli, Stephanie Davidson, Anthony Gineste, Lamia El Guermah, Sabrina Kellouche-Gaillard, et al.. Design and synthesis of a clickable cell-permeable pseudopeptide Pin1 inhibitor with antiproliferative effects on human multiple myeloma cell line. Chemical Communications, 2025, ⟨10.1039/D4CC05968A⟩. ⟨hal-05003977⟩
  • Pieter Langerhorst, Melissa Baerenfaenger, Purva Kulkarni, Simon Nadal, Charissa Wijnands, et al.. N-linked glycosylation of the M-protein variable region: glycoproteogenomics reveals a new layer of personalized complexity in multiple myeloma. Clinical Chemistry and Laboratory Medicine, 2024, 62 (8), pp.1626-1635. ⟨10.1515/cclm-2023-1189⟩. ⟨hal-05085563⟩
  • Somayya Noori, Charissa Wijnands, Pieter Langerhorst, Simon Nadal, Vincent Bonifay, et al.. Minimal Residual Disease Monitoring By Targeted Mass Spectrometry Allows Early Relapse Detection in Multiple Myeloma. Blood, 2022, 140 (Supplement 1), pp.2349-2350. ⟨10.1182/blood-2022-156898⟩. ⟨hal-05085556⟩
  • Severin Lechner, Martin Ian P. Malgapo, Christian Grätz, Raphael Steimbach, Agnes Baron, et al.. Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target. Nature Chemical Biology, 2022, 18 (8), pp.812-820. ⟨10.1038/s41589-022-01015-5⟩. ⟨hal-05085539⟩
  • Brian Josephson, Charlie Fehl, Patrick Isenegger, Simon Nadal, Tom Wright, et al.. Light-driven post-translational installation of reactive protein side chains. Nature, 2020, 585 (7826), pp.530-537. ⟨10.1038/s41586-020-2733-7⟩. ⟨hal-05085267⟩
  • Sebastian Draxler, Margit Bauer, Christian Eickmeier, Simon Nadal, Herbert Nar, et al.. Hybrid Screening Approach for Very Small Fragments: X-ray and Computational Screening on FKBP51. Journal of Medicinal Chemistry, 2020, 63 (11), pp.5856-5864. ⟨10.1021/acs.jmedchem.0c00120⟩. ⟨hal-05085247⟩
  • Simon Nadal, Ritu Raj, Shabaz Mohammed, Benjamin Davis. Synthetic post-translational modification of histones. Current Opinion in Chemical Biology, 2018, 45, pp.35-47. ⟨10.1016/j.cbpa.2018.02.004⟩. ⟨hal-05085237⟩


Thèses

  • Simon Nadal. Studying protein interaction and glycosylation with chemical proteomics. Chemical Sciences. University of Oxford [Oxford], 2020. English. ⟨NNT : ⟩. ⟨tel-05085288⟩