Mehdi BENIDDIR 

Professeur 



Chimie des Substances Naturelles


ahmed-mehdi.beniddir@universite-paris-saclay.fr


0180006343

HM1- 1er étage - 1720


Permanent


https://orcid.org/0000-0003-2153-4290


Research interests :


    

  • Streamlined isolation and structure elucidation of complex natural products.
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  • Absolute configuration assignment.
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His current research aims to develop MS and NMR-based dereplication approaches to detect and characterize natural products from plants and marine invertebrates. Outside the lab, he spends his time running, listening to music, and rowing.
























64 documents







Articles dans une revue61 document




    

  • Mohamed Belemlilga, Hazrina Hazni, Aristide Traore, Indira Dennemont, Sébastien Pomel, et al.. Chemical analysis by molecular networking methods on extracts of Saba senegalensis (A.DC.) Pichon (Apocynaceae) and its anthelmintic activity on Caenorhabditis elegans. Clinical Traditional Medicine and Pharmacology, 2025, 6 (1), pp.200195. ⟨10.1016/j.ctmp.2025.200195⟩. ⟨hal-05149228⟩
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  • Phuong-Y Mai, Élodie Marguerite, Jamal Ouazzani, Philippe Lopes, Pascal Retailleau, et al.. Otitiglycomycins A and B: Glycolipids from the Strain Nocardia otitidiscavarum 20S-13 with Antiviral Activity against Zika Virus. Journal of Natural Products, 2025, 88 (2), pp.485-494. ⟨10.1021/acs.jnatprod.4c01302⟩. ⟨hal-05033142⟩
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  • Rany B. Mbeng Obame, Sidney Gallard, Sacha Gibert, Jean-François Gallard, Solenn Ferron, et al.. Unifying the Absolute Configuration of Dibenzopyrrocoline Alkaloids with Relative Configuration Revision of Cryptowolinol and Description of Isocryptaustoline from Cryptocarya oubatchensis. Journal of Natural Products, 2025, ⟨10.1021/acs.jnatprod.4c01315⟩. ⟨hal-05024657⟩
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  • Louis-Valentin Méteignier, Sarah Szwarc, Patra Barunava, Mickael Durand, Duchesse-Lacours Zamar, et al.. Harnessing the spatial and transcriptional regulation of monoterpenoid indole alkaloid metabolism in Alstonia scholaris leads to the identification of broad geissoschizine cyclase activities. Plant Physiology and Biochemistry, 2025, 219, pp.109363. ⟨10.1016/j.plaphy.2024.109363⟩. ⟨hal-04810555⟩
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  • Sarah Szwarc, Pierre Le Pogam, Mehdi Beniddir. Emerging trends in plant natural products biosynthesis: a chemical perspective. Current Opinion in Plant Biology, 2024, 82, pp.102649. ⟨10.1016/j.pbi.2024.102649⟩. ⟨hal-05058399⟩
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  • Enzo Lezin, Mickael Durand, Caroline Birer Williams, Ana Luisa Lopez Vazquez, Thomas Perrot, et al.. Genome‐based discovery of pachysiphine synthases in Tabernaemontana elegans. The Plant Journal, 2024, 120 (5), pp.1880-1900. ⟨10.1111/tpj.17085⟩. ⟨hal-05036872⟩
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  • Muhammad Tahir Muhammad, Mehdi Beniddir, Lacksany Phongphane, Mohamad Hafizi Abu Bakar, Mohd Hazwan Hussin, et al.. Chemodiverse monoterpene indole alkaloids from Kopsia teoi, inhibitory potential against α-amylase, and their molecular docking studies. Fitoterapia, 2024, 174, pp.105873. ⟨10.1016/j.fitote.2024.105873⟩. ⟨hal-04490024⟩
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  • David Meijer, Mehdi A Beniddir, Connor W Coley, Yassine M Mejri, Meltem Öztürk, et al.. Empowering natural product science with AI: leveraging multimodal data and knowledge graphs. Natural Product Reports, In press, ⟨10.1039/d4np00008k⟩. ⟨hal-04700044⟩
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  • Pierre Le Pogam, Mehdi Beniddir. Structural diversity and chemical logic underlying the assembly of monoterpene indole alkaloids oligomers. Natural Product Reports, 2024, 41 (11), pp.1723-1765. ⟨10.1039/D4NP00011K⟩. ⟨hal-05058404⟩
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  • Sarah Szwarc, Adrien Jagora, Séverine Derbré, Karine Leblanc, Somia Rharrabti, et al.. Combination of Machine Learning and Empirical Computation for the Structural Validation of Trirosaline, a Natural Trimeric Monoterpene Indole Alkaloid from Catharanthus roseus. Organic Letters, 2023, 26 (1), pp.274-279. ⟨10.1021/acs.orglett.3c03972⟩. ⟨hal-04460068⟩
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  • Phuong-Y Mai, Erwan Poupon, Jamal Ouazzani, Rany Mbeng Obame, Philippe Lopes, et al.. Spirobistetrodecamycins A and B: Spontaneous dimeric spiro-fused vinyl cyclobutanes of tetrodecamycin. Tetrahedron, 2023, 149, pp.133712. ⟨10.1016/j.tet.2023.133712⟩. ⟨hal-04403973⟩
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  • Michael Mullowney, Katherine Duncan, Somayah Elsayed, Neha Garg, Justin van der Hooft, et al.. Artificial intelligence for natural product drug discovery. Nature Reviews Drug Discovery, 2023, 22 (11), pp.895-916. ⟨10.1038/s41573-023-00774-7⟩. ⟨hal-04429241⟩
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  • Mehdi Beniddir, Adrien Jagora, Sarah Szwarc, Wassim Hafidi, Jean-François Gallard, et al.. Unifying the configuration of historical alkaloids from Borreria capitata through an extensive spectroscopic reinvestigation. Phytochemistry, 2023, 212, pp.113741. ⟨10.1016/j.phytochem.2023.113741⟩. ⟨hal-04403984⟩
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  • Huibin Wang, Sébastien Halary, Charlotte Duval, Cécile Bernard, Marc Troussellier, et al.. Diversity, metabolome profiling and bioactivities of benthic filamentous cyanobacteria isolated from coastal mangroves of Mayotte. Frontiers in Marine Science, 2023, 10, ⟨10.3389/fmars.2023.1201594⟩. ⟨mnhn-04174558⟩
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  • Elvis Otogo N’nang, Gaëla Cauchie, Pascal Retailleau, Selidji Todagbe Agnandji, Jean-François Gallard, et al.. From the Spectroscopic Reassessment of Authentic Alkaloid Samples to the Molecular Networking-Guided Discovery of Criophylline-Related Analogues from Callichilia inaequalis. Journal of Natural Products, 2023, 86 (5), pp.1202-1210. ⟨10.1021/acs.jnatprod.2c01084⟩. ⟨mnhn-04792947⟩
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  • Elvis Otogo N’nang, Gaëla Cauchie, Pascal Retailleau, Selidji Todagbe Agnandji, Jean-François Gallard, et al.. From the Spectroscopic Reassessment of Authentic Alkaloid Samples to the Molecular Networking-Guided Discovery of Criophylline-Related Analogues from Callichilia inaequalis. Journal of Natural Products, 2023, 86 (5), pp.1202-1210. ⟨10.1021/acs.jnatprod.2c01084⟩. ⟨hal-05058412⟩
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  • Alice Trac, Célia Issaad, Mehdi Beniddir, Jean-Michel Bellanger, Jean-François Gallard, et al.. Ominoxanthone—The First Xanthone Linearly Fused to a γ-Lactone from Cortinarius ominosus Bidaud Basidiomata. CASE- and DFT-Based Structure Elucidation. Molecules, 2023, 28 (4), pp.1557. ⟨10.3390/molecules28041557⟩. ⟨hal-04081617⟩
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  • Norfaizah Osman, Azeana Zahari, Hazrina Hazni, Wan Nurul Nazneem Wan Othman, Nurulfazlina Edayah Rasol, et al.. Isolation and Characterization of Compounds from Ochreinauclea maingayi (Hook. f.) Ridsd. (Rubiaceae) with the Aid of LCMS/MS Molecular Networking. Separations, 2023, 10 (2), pp.74. ⟨10.3390/separations10020074⟩. ⟨hal-04127296⟩
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  • Elvis Otogo N'Nang, Jean-François Gallard, Pierre Champy, Pierre Le Pogam, Mehdi Beniddir, et al.. Density functional theory‐nuclear magnetic resonance‐validated full structure elucidation of theionbrunonine C, an unstable N ‐oxide theionbrunonine from Mostuea brunonis. Magnetic Resonance in Chemistry, 2022, 60 (12), pp.1178-1184. ⟨10.1002/mrc.5271⟩. ⟨hal-04081623⟩
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  • Salemon Akpa Agnès, Timothée Okpekon, Yvette Affoué Kouadio, Adrien Jagora, Dimitri Bréard, et al.. Implementation of a MS/MS database for isoquinoline alkaloids and other annonaceous metabolites. Scientific Data , 2022, 9 (270), pp.1-8. ⟨10.1038/s41597-022-01345-y⟩. ⟨hal-03783707⟩
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  • Pedro Vásquez-Ocmín, Jean-François Gallard, Anne-Cécile van Baelen, Karine Leblanc, Sandrine Cojean, et al.. Biodereplication of Antiplasmodial Extracts: Application of the Amazonian Medicinal Plant Piper coruscans Kunth. Molecules, 2022, 27 (21), pp.7638. ⟨10.3390/molecules27217638⟩. ⟨mnhn-03904753⟩
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  • Andrea Castaldi, Roberta Teta, Germana Esposito, Mehdi A Beniddir, Nicole J de Voogd, et al.. Computational Metabolomics Tools Reveal Subarmigerides, Unprecedented Linear Peptides from the Marine Sponge Holobiont Callyspongia subarmigera. Marine drugs, 2022, 20, ⟨10.3390/md20110673⟩. ⟨mnhn-03858433⟩
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  • Pierre Le Pogam, Nicolas Papon, Mehdi Beniddir, Vincent Courdavault. Computer‐assisted design of sustainable syntheses of pharmaceuticals and agrochemicals from industrial wastes. ChemSusChem, 2022, ⟨10.1002/cssc.202201125⟩. ⟨hal-03741410⟩
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  • Adrien Jagora, Sarah Szwarc, Marc Litaudon, Vincent Dumontet, Jean-François Gallard, et al.. Structure elucidation of an aspidofractinine-type monoterpene indole alkaloid from Melodinus reticulatus. Zeitschrift fur Naturforschung C, 2022, 78 (7-8), pp.271-274. ⟨10.1515/znc-2022-0234⟩. ⟨hal-04081613⟩
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  • Mehdi A Beniddir, Laurence Le Moyec, Mohamed Nawfal Triba, Arlette Longeon, Alexandre Deville, et al.. Metabolomics with Multi-Block Modelling of Mass Spectrometry and Nuclear Magnetic Resonance in order to Discriminate Haplosclerida Marine Sponges. Analytical and Bioanalytical Chemistry, 2022, 414 (19), pp.5929-5942. ⟨10.1007/s00216-022-04158-5⟩. ⟨mnhn-03867254⟩
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  • Hugues Fouotsa, Pierre Mkounga, Alain Meli Lannang, Jérôme Vanheuverzwijn, Zhiyu Zhou, et al.. Pyrrovobasine, hybrid alkylated pyrraline monoterpene indole alkaloid pseudodimer discovered using a combination of mass spectral and NMR-based machine learning annotations. Organic & Biomolecular Chemistry, 2021, 20 (1), pp.98-105. ⟨10.1039/d1ob01791h⟩. ⟨hal-04082218⟩
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  • Juliette Ornely Orango-Bourdette, Mehdi Beniddir, Elvis Otogo N'Nang, Jean-François Gallard, Joseph Privat Ondo, et al.. Structure elucidation of a new lanostane triterpene from Gabonese Ganoderma orbiforme fruiting bodies. Magnetic Resonance in Chemistry, 2021, 59 (11), pp.1165-1170. ⟨10.1002/mrc.5214⟩. ⟨hal-04082185⟩
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  • Hugues Fouotsa, Pierre Le Pogam, Pierre Mkounga, Alain Meli Lannang, Guillaume Bernadat, et al.. Voatriafricanines A and B, Trimeric Vobasine-Aspidosperma-Aspidosperma Alkaloids from Voacanga africana. Journal of Natural Products, 2021, 84 (10), pp.2755-2761. ⟨10.1021/acs.jnatprod.1c00812⟩. ⟨hal-04082176⟩
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  • Adrien Jagora, Jean-François Gallard, Mehdi Beniddir, Pierre Le Pogam. A Reappraisal of the Structure of Lyaline as the First Naturally Occurring Nacycline Monoterpene Indole Alkaloid. Journal of Natural Products, 2021, 84 (9), pp.2617-2622. ⟨10.1021/acs.jnatprod.1c00572⟩. ⟨hal-04082165⟩
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  • Tapé Kouamé, Guillaume Bernadat, Victor Turpin, Marc Litaudon, Aboua Timothée Okpekon, et al.. Structure Reassignment of Melonine and Quantum-Chemical Calculations-Based Assessment of Biosynthetic Scenarios Leading to Its Revised and Original Structures. Organic Letters, 2021, 23 (15), pp.5964-5968. ⟨10.1021/acs.orglett.1c02055⟩. ⟨hal-03470103⟩
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  • Elvis Otogo N’nang, Pierre Le Pogam, Thiery Ndong Mba, Cédric Sima Obiang, Elisabeth Mouray, et al.. Targeted Isolation of Hemitheion from Mostuea brunonis , a Proposed Biosynthetic Intermediate of Theionbrunonines. Journal of Natural Products, 2021, 84 (4), pp.1409-1413. ⟨10.1021/acs.jnatprod.1c00143⟩. ⟨mnhn-03650071⟩
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  • Aurélie Lagarde, Lengo Mambu, Phuong-Y. Mai, Yves Champavier, Jean-Luc Stigliani, et al.. Chlorinated bianthrones from the cyanolichen Nephroma laevigatum. Fitoterapia, 2021, 149, pp.104811. ⟨10.1016/j.fitote.2020.104811⟩. ⟨hal-03203919⟩
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  • Mehdi Beniddir, Kyo Bin Kang, Grégory Genta-Jouve, Florian Huber, Simon Rogers, et al.. Advances in decomposing complex metabolite mixtures using substructure- and network-based computational metabolomics approaches. Natural Product Reports, 2021, 38 (11), pp.1967-1993. ⟨10.1039/D1NP00023C⟩. ⟨hal-05058429⟩
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  • Mehdi Beniddir, Kyo Bin Kang, Grégory Genta-Jouve, Florian Huber, Simon Rogers, et al.. Advances in decomposing complex metabolite mixtures using substructure- and network-based computational metabolomics approaches. Natural Product Reports, 2021, 38 (11), pp.1967-1993. ⟨10.1039/D1NP00023C⟩. ⟨hal-04684581⟩
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  • Amon Diane N'Tamon, Aboua Timothée Okpekon, Nicaise Bony, Guillaume Bernadat, Jean-François Gallard, et al.. Streamlined targeting of Amaryllidaceae alkaloids from the bulbs of Crinum scillifolium using spectrometric and taxonomically-informed scoring metabolite annotations. Phytochemistry, 2020, 179, pp.112485. ⟨10.1016/j.phytochem.2020.112485⟩. ⟨mnhn-02977175⟩
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  • Pierre Le Pogam, Pascal Richomme, Mehdi Beniddir, Thuc-Huy Duong, Guillaume Bernadat, et al.. A thorough evaluation of matrix-free laser desorption ionization on structurally diverse alkaloids and their direct detection in plant extracts. Analytical and Bioanalytical Chemistry, 2020, 412 (27), pp.7405-7416. ⟨10.1007/s00216-020-02872-6⟩. ⟨hal-03014267⟩
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  • Victor Turpin, Mehdi Beniddir, Grégory Genta-Jouve, Adam Skiredj, Jean-François Gallard, et al.. In Silico Anticipation of Metabolic Pathways Extended to Organic Chemistry Reactions: A Case Study with Caffeine Alkaline Hydrolysis and The Origin of Camellimidazoles. Chemistry - A European Journal, 2020, 26 (57), pp.12936-12940. ⟨10.1002/chem.202002196⟩. ⟨hal-04082710⟩
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  • Gaëla Cauchie, Elvis Otogo N'Nang, Justin van der Hooft, Pierre Le Pogam, Guillaume Bernadat, et al.. Phenylpropane as an Alternative Dearomatizing Unit of Indoles: Discovery of Inaequalisines A and B Using Substructure-Informed Molecular Networking. Organic Letters, 2020, 22 (15), pp.6077-6081. ⟨10.1021/acs.orglett.0c02153⟩. ⟨hal-04082717⟩
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  • Tapé Kouamé, Aboua Timothée Okpekon, Nicaise Bony, Amon Diane N’tamon, Jean-François Gallard, et al.. Corynanthean-Epicatechin Flavoalkaloids from Corynanthe pachyceras. Molecules, 2020, Natural Products Chemistry, 25 (11), pp.2654. ⟨10.3390/molecules25112654⟩. ⟨mnhn-02867368⟩
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  • Charlotte Fox Alcover, Guillaume Bernadat, Faustin Kabran, Pierre Le Pogam, Karine Leblanc, et al.. Molecular Networking Reveals Serpentinine-Related Bisindole Alkaloids from Picralima nitida, a Previously Well-Investigated Species. Journal of Natural Products, 2020, 83 (4), pp.1207-1216. ⟨10.1021/acs.jnatprod.9b01247⟩. ⟨hal-04082731⟩
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  • Sébastien Duperron, Mehdi A Beniddir, Sylvain Durand, Arlette Longeon, Charlotte Duval, et al.. New Benthic Cyanobacteria from Guadeloupe Mangroves as Producers of Antimicrobials. Marine drugs, 2020, ⟨10.3390/md18010016⟩. ⟨mnhn-02423405⟩
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  • Van-Kieu Nguyen, Grégory Genta-Jouve, Thuc-Huy Duong, Mehdi Beniddir, Jean-François Gallard, et al.. Eumitrins C-E: Structurally diverse xanthone dimers from the vietnamese lichen Usnea baileyi. Fitoterapia, 2020, 141, pp.104449. ⟨10.1016/j.fitote.2019.104449⟩. ⟨hal-04082737⟩
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  • Siguara Bastos Lemos Silva, Mehdi Beniddir, Jean‐françois Gallard, Erwan Poupon, Olivier Thomas, et al.. Chemical Insights into the Anchinopeptolide Series. European Journal of Organic Chemistry, 2019, 2019 (31-32), pp.5515-5518. ⟨10.1002/ejoc.201900625⟩. ⟨hal-03575266⟩
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  • Alexander E Fox Ramos, Coralie Pavesi, Marc Litaudon, Vincent Dumontet, Erwan Poupon, et al.. CANPA: Computer-Assisted Natural Products Anticipation. Analytical Chemistry, 2019, 91 (17), pp.11247 - 11252. ⟨10.1021/acs.analchem.9b02216⟩. ⟨hal-03353431⟩
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  • E. Ramos, Pierre Le Pogam, Charlotte Fox Alcover, Elvis Otogo N'Nang, Gaëla Cauchie, et al.. Collected mass spectrometry data on monoterpene indole alkaloids from natural product chemistry research. Scientific Data , 2019, 6 (15), pp.1-6. ⟨10.1038/s41597-019-0028-3⟩. ⟨hal-02861053⟩
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  • James B. Mcalpine, Shao-Nong Chen, Andrei Kutateladze, John Macmillan, Giovanni Appendino, et al.. The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports, 2019, 36 (1), pp.35-107. ⟨10.1039/c7np00064b⟩. ⟨hal-01995061⟩
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  • Thi Phuong Thuy Hoang, Catherine Roullier, Marie-Claude Boumard, Thibaut Robiou Du Pont, Hassan Nazih, et al.. Metabolomics-Driven Discovery of Meroterpenoids from a Mussel-Derived Penicillium ubiquetum. Journal of Natural Products, 2018, 81 (11), pp.2501-2511. ⟨10.1021/acs.jnatprod.8b00569⟩. ⟨hal-03015858⟩
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  • Elvis Otogo N’nang, Guillaume Bernadat, Elisabeth Mouray, Brice Kumulungui, Philippe Grellier, et al.. Theionbrunonines A and B: Dimeric Vobasine Alkaloids Tethered by a Thioether Bridge from Mostuea brunonis. Organic Letters, 2018, 20 (20), pp.6596-6600. ⟨10.1021/acs.orglett.8b02961⟩. ⟨mnhn-02022725⟩
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  • Nicolas Duchemin, Adam Skiredj, Justine Mansot, Karine Leblanc, Jean-Jacques Vasseur, et al.. DNA-Templated [2+2] Photocycloaddition: A Straightforward Entry into the Aplysinopsin Family of Natural Products. Angewandte Chemie International Edition, 2018, 57 (36), pp.11786-11791. ⟨10.1002/anie.201806357⟩. ⟨hal-02197152⟩
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  • Elvis Otogo N’nang Obiang, Grégory Genta-Jouve, Jean-François Gallard, Brice Kumulungui, Elisabeth Mouray, et al.. Pleiokomenines A and B: Dimeric Aspidofractinine Alkaloids Tethered with a Methylene Group. Organic Letters, 2017, 19 (22), pp.6180-6183. ⟨10.1021/acs.orglett.7b03098⟩. ⟨hal-01966401⟩
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  • Alexander Fox Ramos, Charlotte Alcover, Laurent Evanno, Marc Litaudon, Christophe Duplais, et al.. Beyond the “Code”: A Guide to the Description and Documentation of Biodiversity in Ciliated Protists (Alveolata, Ciliophora). Journal of Eukaryotic Microbiology, 2017, 64 (4), pp.539-554. ⟨10.1111/jeu.12391⟩. ⟨hal-02134404⟩
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  • Alexander Fox Ramos, Charlotte Alcover, Laurent Evanno, Alexandre Maciuk, Marc Litaudon, et al.. Revisiting Previously Investigated Plants: A Molecular Networking-Based Study of Geissospermum laeve. Journal of Natural Products, 2017, 80 (4), pp.1007-1014. ⟨10.1021/acs.jnatprod.6b01013⟩. ⟨hal-02105819⟩
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  • David Lachkar, Natacha Denizot, Guillaume Bernadat, Kadiria Ahamada, Mehdi Beniddir, et al.. Unified biomimetic assembly of voacalgine A and bipleiophylline via divergent oxidative couplings. Nature Chemistry, 2017, 9 (8), pp.793-798. ⟨10.1038/nchem.2735⟩. ⟨hal-05115363⟩
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  • Adam Skiredj, Mehdi Beniddir, Laurent Evanno, Erwan Poupon. Mimicking the Main Events of the Biosynthesis of Drimentines: Synthesis of Δ8′‐Isodrimentine A and Related Compounds. European Journal of Organic Chemistry, 2016, 2016 (17), pp.2954-2958. ⟨10.1002/ejoc.201600444⟩. ⟨hal-05114436⟩
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  • Mehdi Beniddir, Laurent Evanno, Delphine Joseph, Adam Skiredj, Erwan Poupon. Emergence of diversity and stereochemical outcomes in the biosynthetic pathways of cyclobutane-centered marine alkaloid dimers. Natural Product Reports, 2016, 33 (7), pp.820-842. ⟨10.1039/c5np00159e⟩. ⟨hal-05114432⟩
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  • Adam Skiredj, Mehdi Beniddir, Delphine Joseph, Guillaume Bernadat, Laurent Evanno, et al.. Harnessing the Intrinsic Reactivity within the Aplysinopsin Series for the Synthesis of Intricate Dimers: Natural from Start to Finish. Synthesis: Journal of Synthetic Organic Chemistry, 2015, 47 (16), pp.2367-2376. ⟨10.1055/s-0034-1381032⟩. ⟨hal-05114461⟩
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  • Sarah Benayad, Mehdi Beniddir, Laurent Evanno, Erwan Poupon. Biomimetic Assembly of Leucoridine A. European Journal of Organic Chemistry, 2015, 2015 (9), pp.1894-1898. ⟨10.1002/ejoc.201500041⟩. ⟨hal-05114457⟩
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  • Adam Skiredj, Mehdi Beniddir, Delphine Joseph, Karine Leblanc, Guillaume Bernadat, et al.. A Unified Bioinspired “Aplysinopsin Cascade”: Total Synthesis of (±)-Tubastrindole B and Related Biosynthetic Congeners. Organic Letters, 2014, 16 (19), pp.4980-4983. ⟨10.1021/ol502177m⟩. ⟨hal-05114466⟩
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  • Adam Skiredj, Mehdi Beniddir, Delphine Joseph, Karine Leblanc, Guillaume Bernadat, et al.. Spontaneous Biomimetic Formation of (±)‐Dictazole B under Irradiation with Artificial Sunlight. Angewandte Chemie International Edition, 2014, 53 (25), pp.6419-6424. ⟨10.1002/anie.201403454⟩. ⟨hal-05114474⟩
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  • Sylvie Morel, Jean-Jacques Helesbeux, Denis Séraphin, Séverine Derbré, Julia Gatto, et al.. Anti-AGEs and antiparasitic activity of an original prenylated isoflavonoid and flavanones isolated from Derris ferruginea. Phytochemistry Letters, 2013, 6 (3), pp.498-503. ⟨10.1016/j.phytol.2013.06.002⟩. ⟨hal-00911058⟩
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  • Mehdi Beniddir, Marie-Thérèse Martin, Marie-Elise Tran Huu Dau, Philippe Grellier, Philippe Rasoanaivo, et al.. Goniomedines A and B: Unprecedented Bisindole Alkaloids Formed through Fusion of Two Indole Moieties via a Dihydropyran Unit. Organic Letters, 2012, 14 (16), pp.4162-4165. ⟨10.1021/ol301832t⟩. ⟨mnhn-02047389⟩
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Communications dans un congrès1 document




    

  • Yassine M Mejri, Mehdi A Beniddir, Olivier Cailloux, Meltem Öztürk. Experimental evaluation of similarity indices about the MIA molecular family. Multiple-Criteria Decision Aid to Preference Learning, Nov 2022, Compiègne, France. ⟨hal-04272008⟩
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Chapitres d'ouvrage1 document




    

  • Pierre Le Pogam, Erwan Poupon, Pierre Champy, Mehdi Beniddir. Implementation of an MS/MS Spectral Library for Monoterpene Indole Alkaloids. Catharanthus roseus, 2505, Springer US, pp.87-100, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2349-7_7⟩. ⟨hal-05058417⟩
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Pré-publications, Documents de travail1 document




    

  • Yassine Mejri, Olivier Cailloux, Elvis Otogo N'Nang, Blandine Séon-Méniel, Jean-François Gallard, et al.. MS2DECIDE: Aggregating Multi-Annotated Tandem Mass Spectrometry Data with Decision Theory Enhances Natural Products Prioritization. 2025. ⟨hal-05058403⟩
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Documents récupérés de l'archive ouverte HAL logo




Mehdi graduated in Pharmacy and received his M.Sc. degree from Université Paris-Sud in 2009. He obtained his Ph.D. under the guidance of Drs. Françoise Guéritte and Marc Litaudon at Institut de Chimie des Substances Naturelles, (ICSN-CNRS) in 2012. He was subsequently a post-doctoral fellow of Prof. Erwan Poupon at Université Paris-Sud, where he became an assistant professor in Pharmacognosy in 2014.


Education :


    

  • 2022 Professor of Pharmacognosy, Paris-Saclay University.
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  • 2019 Habilitation, Paris-Saclay University.
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  • 2014 Associate Professor of Pharmacognosy, Paris-Saclay University.
    • 

  • 2012-2014 Post Doctoral Researcher, Paris-Sud University (France) with Prof. Erwan Poupon.
    – 2009-2012 Ph. D. Chemistry of Natural Products, Paris-Sud University, ICSN-CNRS (Supervision : Dr. Marc Litaudon and Dr. Françoise Guéritte), France.
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  • 2007-2009 M.Sc : Synthesis, pharmaceutical chemistry and natural products R&D, Paris-Sud University, France.
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  • 2002-2007 Pharm. D. University of Algiers, Algeria.
    •