Chiara ZANATO 

Maîtresse de Conférences 



Chimie Biologique, Permanent


chiara.zanato@cyu.fr




Site de Cergy


Permanent


https://orcid.org/0000-0002-9132-5120


Organic Chemistry, Medicinal Chemistry, Chemical Biology


PROTACs

Synthesis of bioactive molecules as molecular tools for studying biological processes

Peptides and Pseudopeptides

Total Synthesis of natural compounds

18F-labeled PET tracers

Cannabinoids Receptors
























9 documents







Articles dans une revue7 document




    

  • Lorenzo Meneghelli, Stephanie Davidson, Anthony Gineste, Lamia El Guermah, Sabrina Kellouche-Gaillard, et al.. Design and synthesis of a clickable cell-permeable pseudopeptide Pin1 inhibitor with antiproliferative effects on human multiple myeloma cell line. Chemical Communications, 2025, ⟨10.1039/D4CC05968A⟩. ⟨hal-05003977⟩
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  • Nathan Picois, Yazid Boutahri, Pierre Milbeo, Chiara Zanato, Nathalie Lensen, et al.. Asymmetric α-Fluoroalkyl-α-Amino Acids: Recent Advances in Their Synthesis and Applications. Molecules, 2024, 29 (6), pp.1408. ⟨10.3390/molecules29061408⟩. ⟨hal-04516441⟩
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  • Dongxu Zhai, Shuxin Yan, James Samsom, Le Wang, Ping Su, et al.. Small-molecule targeting AMPA-mediated excitotoxicity has therapeutic effects in mouse models for multiple sclerosis. Science Advances , 2023, 9 (49), ⟨10.1126/sciadv.adj6187⟩. ⟨hal-04604036⟩
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  • Karen Thompson, Sonia Watson, Chiara Zanato, Sergio Dall'Angelo, Joriene de Nooij, et al.. The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2. Experimental Physiology, 2023, ⟨10.1113/EP090761⟩. ⟨hal-04273805⟩
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  • Khoubaib Ben Haj Salah, Francesco Terzani, Marine Pietri, Chiara Zanato, Evelyne Chelain, et al.. Highly stereoselective multigram scale synthesis of (3S,4S)-Statine and (3S,4S)-N-Benzylstatine. Results in Chemistry, 2022, 4, pp.100333. ⟨10.1016/j.rechem.2022.100333⟩. ⟨hal-04098168⟩
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  • Monica Piras, Ilaria Patruno, Christina Nikolakopoulou, Janet Willment, Nikki Sloan, et al.. Synthesis of the Fungal Metabolite YWA1 and Related Constructs as Tools to Study MelLec-Mediated Immune Response to Aspergillus Infections. Journal of Organic Chemistry, 2021, 86 (9), pp.6044-6055. ⟨10.1021/acs.joc.0c02324⟩. ⟨hal-03630255⟩
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  • Mark Stappers, Alexandra Clark, Vishukumar Aimanianda, Stefan Bidula, Delyth Reid, et al.. Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus. Nature, 2018, 555 (7696), pp.382-386. ⟨10.1038/nature25974⟩. ⟨pasteur-02501369⟩
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Proceedings/Recueil des communications1 document




    

  • Lorenzo Meneghelli, Lamia El Guermah, Maud Larregola, Sabrina Kellouche-Gaillard, Franck Carreiras, et al.. Design and Synthesis of Pin1-PROTACs as Potential Therapeutic Tools for Cancer Treatment. 36th European Peptide Symposium, Aug 2022, Sitges (Barcelona), Spain. The European Peptide Society, pp.285-287, 2022, ⟨10.17952/36EPS/36EPS.2022.285⟩. ⟨hal-05003974⟩
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Habilitations à diriger des recherches1 document




    

  • Chiara Zanato. From total synthesis to chemical biology: an overview of my scientific career. Chemical Sciences. CYU Cergy Paris Université, 2024. ⟨tel-05012925⟩
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2005 – BSc in Chemistry at the University of Milan (Italy)

2007 – MSc in Chemical Sciences at the University of Milan (Italy)

2007 – 2010: PhD in Organic Chemistry (group of Professor C.Gennari) University of Milan (Italy)

2011 – 2017: Research fellow (group of Professor M. ZANDA), University of Aberdeen (UK)

2017 – 2018: Postdoc (group of Professor T. BRIGAUD) at BioCIS, CY Cergy Paris Université (FR)

2018 – 2020: Ingénieur de Recherche at BioCIS, CY Cergy Paris Université (FR)

2020 –Present: Associate Professor at BioCIS, CY Cergy Paris Université (FR)