Olivier PROVOT 

Maître de Conférences 



CoSMIT


olivier.provot@universite-paris-saclay.fr


0180006405

HM1- 1er étage - 1511


Permanent


https://orcid.org/0000-0002-4985-116X
























33 documents







Articles dans une revue33 document




    

  • Mouad Alami, Olivier Provot. Recent advances in the synthesis of dibenzofurans. Organic & Biomolecular Chemistry, 2024, 22 (7), pp.1323-1345. ⟨10.1039/D3OB01736B⟩. ⟨hal-04478438⟩
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  • Olivier Provot. Novel access to α-carbolines with biological applications. European Journal of Medicinal Chemistry, 2024, 276, pp.116700. ⟨10.1016/j.ejmech.2024.116700⟩. ⟨hal-04697354⟩
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  • Xinya Liu, Jean-Luc Pozzo, Abdallah Hamze, Mouad Alami, Olivier Provot. Hydration of Unsymmetrical Internal Alkynes: Factors Governing the Regioselectivity. ACS Catalysis, In press, pp.10115-10136. ⟨10.1021/acscatal.9b00482⟩. ⟨hal-04167995⟩
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  • Yunxin Yao, Guangkuan Zhao, Abdallah Hamze, Mouad Alami, Olivier Provot. Mild Deprotection of Dithioacetals by TMSCl/NaI Association in CH3CN. European Journal of Organic Chemistry, 2022, 2022 (7), pp.5775-5779. ⟨10.1002/ejoc.202101460⟩. ⟨hal-04279896⟩
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  • Yunxin Yao, Mouad Alami, Abdallah Hamze, Olivier Provot. Recent Advances in the Synthesis of Pyrido[1,2-a]indoles. Organic & Biomolecular Chemistry, 2021, 19 (16), pp.3509-3526. ⟨10.1039/D1OB00153A⟩. ⟨hal-03349116⟩
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  • Shannon Pecnard, Abdallah Hamze, Jean-Luc Pozzo, Mouad Alami, Olivier Provot. Synthesis of Oxazino[4,3-a]indoles and Biological Applications. European Journal of Medicinal Chemistry, 2021, 224, pp.113728. ⟨10.1016/j.ejmech.2021.113728⟩. ⟨hal-03349152⟩
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  • Shannon Pecnard, Olivier Provot, Hélène Levaique, Jérome Bignon, Laurie Askenatzis, et al.. Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation. European Journal of Medicinal Chemistry, 2021, 209, pp.112873. ⟨10.1016/j.ejmech.2020.112873⟩. ⟨hal-03034493⟩
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  • Shannon Pecnard, Abdallah Hamze, Jérome Bignon, Bastien Prost, Alain Deroussent, et al.. Anticancer Properties of Indole Derivatives as IsoCombretastatin A-4 analogues. European Journal of Medicinal Chemistry, 2021, 223, pp.113656. ⟨10.1016/j.ejmech.2021.113656⟩. ⟨hal-03349143⟩
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  • Kena Zhang, Christine Tran, Mouad Alami, Abdallah Hamze, Olivier Provot. Synthesis and biological activities of pyrazino[1,2-a]indole and pyrazino[1,2-a]indol-1-one derivatives. Pharmaceuticals, 2021, 14 (8), pp.779. ⟨10.3390/ph14080779⟩. ⟨hal-03349178⟩
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  • Yunxin Yao, Guangkuan Zhao, Abdallah Hamze, Mouad Alami, Olivier Provot. Mild Deprotection of Dithioacetals by TMSCl/NaI Association in CH3CN. European Journal of Organic Chemistry, In press, ⟨10.1002/ejoc.202000979⟩. ⟨hal-02910296⟩
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  • Ilhem Khelifi, Shannon Pecnard, Guillaume Bernadat, Jérôme Bignon, Hélène Levaique, et al.. Synthesis and Anticancer Properties of Oxazepines Related to Azaisoerianin and IsoCoQuines. ChemMedChem, 2020, ⟨10.1002/cmdc.202000197⟩. ⟨hal-02910295⟩
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  • Alexandra Bordes, Isabelle Opalinski, Fabien Thoreau, Olivier Provot, Mouad Alami, et al.. β-Glucuronidase-Responsive Albumin-Binding Prodrug of Colchicine-Site Binders for Selective cancer Therapy. ChemMedChem, 2020, ⟨10.1002/cmdc.202400969⟩. ⟨hal-04918349⟩
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  • Guangkuan Zhao, Mingxiang Zhu, Olivier Provot, Mouad Alami, Samir Messaoudi. Synthesis of 2,3-Substituted β- N -Glycosyl Indoles through C–H Activation/Annulation Process under Rh(III)-Catalysis. Organic Letters, 2020, 22 (1), pp.57-61. ⟨10.1021/acs.orglett.9b03893⟩. ⟨hal-03036320⟩
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  • Timothée Naret, Ilhem Khelifi, Olivier Provot, Jérôme Bignon, Hélène Lévaique, et al.. 1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation. Journal of Medicinal Chemistry, 2019, 62 (4), pp.1902-1916. ⟨10.1021/acs.jmedchem.8b01386⟩. ⟨hal-02123778⟩
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  • Guangkuan Zhao, Christelle Roudaut, Vincent Gandon, Mouad Alami, Olivier Provot. Synthesis of 2-Substituted Indoles through Cyclization and Demethylation of 2-Alkynyldimethylanilines by Ethanol. Green Chemistry, 2019, 21 (15), pp.4204-4210. ⟨10.1039/c9gc01880h⟩. ⟨hal-03349087v2⟩
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  • Ilhem Khelifi, Guangkuan Zhao, Nour-Eddine Ghermani, Olivier Provot, Mouad Alami. Unexpected Oxidative Ring Opening of Electron-Rich 3-Aminobenzofurans into α-Ketoimines Derivatives. Journal of Organic Chemistry, 2019, 84 (4), pp.1725-1733. ⟨10.1021/acs.joc.8b01685⟩. ⟨hal-02394232⟩
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  • Ilhem Khelifi, Timothée Naret, Abdallah Hamze, Jérôme Bignon, Hélène Lévaique, et al.. N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents. European Journal of Medicinal Chemistry, 2019, 168, pp.176-188. ⟨10.1016/j.ejmech.2019.02.038⟩. ⟨hal-02394208⟩
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  • Guangkuan Zhao, Ling-Zhi Yuan, Mouad Alami, Olivier Provot. Chlorotrimethylsilane and Sodium Iodide: A Remarkable Metal-Free Association for the Desulfurization of Benzylic Dithioketals under Mild Conditions. Advanced Synthesis and Catalysis, 2018, 360 (13), pp.2522-2536. ⟨10.1002/adsc.201800437⟩. ⟨hal-02394255⟩
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  • Guangkuan Zhao, Jérôme Bignon, Hélène Lévaique, Joëlle Dubois, Mouad Alami, et al.. One-Pot Synthesis of 2-Styrylindoles from Ortho -Substituted Chloroenynes. Journal of Organic Chemistry, 2018, 83 (24), pp.15323-15332. ⟨10.1021/acs.joc.8b02563⟩. ⟨hal-02394175⟩
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  • Guangkuan Zhao, Ling-Zhi Yuan, Mouad Alami, Olivier Provot. Desulfurization of Thioketals into Methylene and Methyl Derivatives: Nickel or not Nickel?. ChemistrySelect, 2017, 2 (33), pp.10951-10959. ⟨10.1002/slct.201702370⟩. ⟨hal-02394278⟩
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  • Ling-Zhi Yuan, Guangkuan Zhao, Abdallah Hamze, Mouad Alami, Olivier Provot. Chlorotrimethylsilane and Sodium Iodide: A Useful Combination for the Regioselective Deoxygenation of Arylalkyl-α-Diketones. Advanced Synthesis and Catalysis, 2017, 359 (15), pp.2682-2691. ⟨10.1002/adsc.201700276⟩. ⟨hal-02394293⟩
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  • Guangkuan Zhao, Mouad Alami, Olivier Provot. Synthesis and Functionalization of 3-Bromo-2-(2- chlorovinyl)benzothiophenes as Molecular Tools. RSC Advances, 2017, 73, ⟨10.1039/C7RA07340B⟩. ⟨hal-02910292⟩
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  • Guangkuan Zhao, Mouad Alami, Olivier Provot. Synthesis and functionalization of 3-bromo-2-(2-chlorovinyl)benzothiophenes as molecular tools. RSC Advances, 2017, 7 (73), pp.46007-46013. ⟨10.1039/c7ra07340b⟩. ⟨hal-02394339⟩
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  • Guangkuan Zhao, Ling-Zhi Yuan, Mylène Roudier, Jean-François Peyrat, Abdallah Hamze, et al.. A Convenient Metal-Free Synthesis of (E)-3-Styrylisocoumarins through Annulation of (E)-1,4-Diarylenynes. Synthesis: Journal of Synthetic Organic Chemistry, 2016, 48 (19), pp.3382-3392. ⟨10.1055/s-0035-1562501⟩. ⟨hal-02394350⟩
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  • Olivier Provot, Abdallah Hamze, Jean-François Peyrat, Jean-Daniel Brion, Mouad Alami. Discovery and Hit to Lead Optimization of Novel Combretastatin A-4 Analogues: Dependence of C-Linker Length and Hybridization. Anti-Cancer Agents in Medicinal Chemistry, 2013, 13 (10), pp.1614-1635. ⟨10.2174/187152061310131206162302⟩. ⟨hal-02394384⟩
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  • Maud Jacubert, Olivier Provot, Jean-François Peyrat, Abdallah Hamze, Jean-Daniel Brion, et al.. p-Toluenesulfonic acid-promoted selective functionalization of unsymmetrical arylalkynes: a regioselective access to various arylketones and heterocycles. Tetrahedron, 2010, 66 (21), pp.3775-3787. ⟨10.1016/j.tet.2010.03.055⟩. ⟨hal-02394573⟩
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  • Samir Messaoudi, Bret Tréguier, Abdallah Hamze, Olivier Provot, Jean-François Peyrat, et al.. Isocombretastatins a versus combretastatins a: the forgotten isoCA-4 isomer as a highly promising cytotoxic and antitubulin agent.. Journal of Medicinal Chemistry, 2009, 52 (14), pp.4538-42. ⟨10.1021/jm900321u⟩. ⟨hal-00421101⟩
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  • Abdallah Hamze, Anne Giraud, Samir Messaoudi, Olivier Provot, Jean-François Peyrat, et al.. Synthesis, Biological Evaluation of 1,1-Diarylethylenes as a Novel Class of Antimitotic Agents. ChemMedChem, 2009, 4 (11), pp.1912-1924. ⟨10.1002/cmdc.200900290⟩. ⟨hal-02394586⟩
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  • Gaëlle Le Bras, Olivier Provot, Jean-François Peyrat, Mouad Alami, Jean-Daniel Brion. Rapid microwave assisted hydration of internal arylalkynes in the presence of PTSA: an efficient regioselective access to carbonyl compounds. Tetrahedron Letters, 2006, 47 (31), pp.5497-5501. ⟨10.1016/j.tetlet.2006.05.155⟩. ⟨hal-02394618⟩
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  • Nathalie L'Hermite, Anne Giraud, Olivier Provot, Jean-François Peyrat, Mouad Alami, et al.. Disproportionation reaction of diarylcarbinols: a versatile access to diarylmethanes speeded up using microwave irradiation. Tetrahedron, 2006, 62 (51), pp.11994-12002. ⟨10.1016/j.tet.2006.09.083⟩. ⟨hal-02394612⟩
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  • Gaëlle Le Bras, Olivier Provot, Alain Bekaert, Jean-François Peyrat, Mouad Alami, et al.. α-Iodination of Ketones with MnO 2 /I 2 Reagent Combination: A New Environmentally Friendly Procedure. Synthesis: Journal of Synthetic Organic Chemistry, 2006, 2006 (9), pp.1537-1541. ⟨10.1055/s-2006-926435⟩. ⟨hal-02394625⟩
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  • Anne Giraud, Olivier Provot, Jean-François Peyrat, Mouad Alami, Jean-Daniel Brion. Microwave-assisted efficient synthesis of 1,2-diaryldiketones: a novel oxidation reaction of diarylalkynes with DMSO promoted by FeBr3. Tetrahedron, 2006, 62 (33), pp.7667-7673. ⟨10.1016/j.tet.2006.05.072⟩. ⟨hal-02394615⟩
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  • Olivier Provot, Anne Giraud, Jean-François Peyrat, Mouad Alami, Jean-Daniel Brion. Synthetic approach to enyne and enediyne analogues of anticancer agents. Tetrahedron Letters, 2005, 46 (49), pp.8547-8550. ⟨10.1016/j.tetlet.2005.10.001⟩. ⟨hal-02394628⟩
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