Research interests

Chiral fluorinated compounds (amino acids, pseudopeptides, amino alcohols, amines, diamines….), synthesis of fluorinated peptides and biological applications (inhibition of amyloid peptides aggregation, nociception, antimicrobial peptides, proteases inhibition…)

https://www.cyu.fr/m-thierry-brigaud

Education & Career :

• PhD (1990): University Claude Bernard, Lyon I, direction Prof. E. Laurent
• Post-doc (1990-1991): State University of New York at Stony Brook, USA, (Prof. I. Ojima)
• Associate Professor (1991-2002): Université de Reims-Champagne-Ardenne, UMR 6519 (Prof. C. Portella’s group). Habilitation in 1999.
• Full Professor (2002-present):Cergy Paris Université University of Cergy-Pontoise
• Director of the Laboratory of Chemical Biology (LCB, EA 4505) from 1/10/2012 to 31/12/2019 and director of the Chemical Biology Team of BioCIS
• Deputy director of BioCIS (UMR-CNRS-8076)  from 1/01/2020
• Direction of the organofluorine group of the Chemical Biology Team of BioCIS

Other activities

• Professor of organic chemistry
• Director of the second year in physics – chemistry – earth sciences of the University of Cergy-Pontoise 2005-2017
• Member of the organizing committees of 14 national and international symposiums.
• Member of the international advisory board of the 18th European Symposium on Fluorine Chemistry. Kiev, August 7-12 2016.
• Coordinator of the fluorine and life science section of the French Fluorine Network (GIS CNRS)
• Associate editor of Frontiers in Chemistry – Organic Chemistry section
• Guest editor of The Journal of Fluorine Chemistry (Special issue of the 2014 Bordeaux Fluorine Days)
• Member of the selection committee of the ANR SIMI 7 (2012, 2013)
• Expert for the ANR (Blanc, JCJC, PCV, émergence, grand défis sociétaux, MRSI)
• Advisor for Central Glass Company (Japan)
• Expert for ERC, fonds québécois de recherche sur la nature et les technologies, Royal Chemical Society, Israel Science Foundation, Humboldt Foundation, Fulbright Foundation, Research Council Romania …
• Member of the scientific council (2008-2012) and the studies council (2006-2008) of the University of Cergy-Pontoise
• Member of more than 20 University selection committees, 71 PhD and habilitation committees

Funded projects

• Coordinator of a French – Bulgarian program RILA : Analgesic effects of MIF-analogues containing CF3-prolines or CF3-pseudoprolines
• Coordinator of the ANR-DFG 2012-2015 “CF3-Peptaibols” in collaboration with the group of Prof Anne S. Ulrich (Karlsruhe Institute of Technology)
• Isite Paris-Seine Post-doc program 2017
• Projet SESAME Région IDF ROMANCE (RMN)
• Coordinator of the ANR 2019-2022 “F-LAIR”
• 2 EUTOPIA PhD cotutelle (University of Ljubljana andVrije University of Brussel)
• Coordinator of the INEX Ambition project Biomol