CROUSSE

Dimitra Kyrko, Tingting Cao, Pascal Retailleau, Julia Kaffy, Benoît Crousse. Access to N -Fluorinated Azapeptides and Azapeptoids as Peptidomimetic Scaffolds. ACS Organic & Inorganic Au, 2025, ⟨10.1021/acsorginorgau.5c00073⟩. ⟨hal-05248269⟩
Monika Skibinska, Alicja Warowicka, Benoît Crousse, Tomasz Cytlak. Synthesis and Antibacterial Activity of Novel Phosphonated CF 3 -β-lactams. ACS Omega, 2025, 10 (17), pp.18062-18072. ⟨10.1021/acsomega.5c01562⟩. ⟨hal-05105385⟩
Thierry Milcent, Pascal Retailleau, Benoit Crousse, Sandrine Ongeri. Synthesis of extended fluorinated tripeptides based on the tetrahydropyridazine scaffold. Beilstein Journal of Organic Chemistry, 2024, 20, pp.3174-3181. ⟨10.3762/bjoc.20.262⟩. ⟨hal-05142142⟩
Dimitra Kyrko, Murat Saraç, Jing Hao, Pascal Retailleau, Sandrine Ongeri, et al.. Functionalized α‐Fluorinated Amines from Imines and Enol Ethers. Advanced Synthesis and Catalysis, 2024, 366 (16), pp.3460-3465. ⟨10.1002/adsc.202400517⟩. ⟨hal-04756974⟩
Monika Skibinska, Alicja Warowicka, Henryk Koroniak, Tomasz Cytlak, Benoît Crousse. Synthesis, Reactivity, and Antibacterial Activity of gem -Difluoroalkene, Difluoromethyl, and Trifluoromethyl β-Lactams. Organic Letters, 2024, 26 (3), pp.692-696. ⟨10.1021/acs.orglett.3c04094⟩. ⟨hal-04756963⟩
José Laxio Arenas, Jacopo Lesma, Tap Ha‐duong, Bikash Ranjan Sahoo, Ayyalusamy Ramamoorthy, et al.. Composition and Conformation of Hetero‐ versus Homo‐Fluorinated Triazolamers Influence their Activity on Islet Amyloid Polypeptide Aggregation. Chemistry - A European Journal, 2024, 30 (28), pp.e202303887. ⟨10.1002/chem.202303887⟩. ⟨hal-04756674⟩
Benoît Crousse. Recent Advances in the Syntheses of N ‐CF 3 Scaffolds up to Their Valorization. Chemical Record, 2023, 23 (9), ⟨10.1002/tcr.202300011⟩. ⟨hal-04756947⟩
Sondes Ghrairi, Pascal Retailleau, Benoit Crousse, Thouraya Barhoumi-Slimi. A one-pot synthesis and X-Ray structural characterization of new highly substituted-allyl carbamates. Journal of Molecular Structure, 2022, 1258, pp.132548. ⟨10.1016/j.molstruc.2022.132548⟩. ⟨hal-03796662⟩
Benoit Crousse, Tingting Cao. Direct access to fluorinated sulfonylhydrazides and study of their reactivity in thiolation reaction on indoles. Helvetica Chimica Acta, 2022, 105 (3), ⟨10.1002/hlca.202100196⟩. ⟨hal-04249482⟩
José Laxio Arenas, Pascal Retailleau, Jean-Michel Gillet, Nour-Eddine Ghermani, Sandrine Ongeri, et al.. 5-Fluoro-1,2,3-triazole motif in peptides and its electronic properties. Organic & Biomolecular Chemistry, 2022, 20 (43), pp.8410-8414. ⟨10.1039/D2OB01716D⟩. ⟨hal-04249450⟩
Tingting Cao, Pascal Retailleau, Thierry Milcent, Benoît Crousse. Synthesis of N-CF3 hydrazines through radical trifluoromethylation of azodicarboxylates. Chemical Communications, In press, ⟨10.1039/D1CC04538E⟩. ⟨hal-03368341⟩
Sondes Ghrairi, Khaled Essalah, Benoit Crousse, Thouraya Barhoumi-Slimi. β-chlorovinylaldehydes as intermediates in the synthesis of new substituted β–fluoroalkoxyvinyl aldehydes and corresponding alcohols. Journal of Fluorine Chemistry, 2021, 248, ⟨10.1016/j.jfluchem.2021.109837⟩. ⟨hal-03796609⟩
José Laxio Arenas, Yaochun Xu, Thierry Milcent, Carine van Heijenoort, Francois Giraud, et al.. Fluorinated Triazole Foldamers: folded or extended conformational preferences. ChemPlusChem, 2021, ⟨10.1002/cplu.202000791⟩. ⟨hal-03796604⟩
José Laxio Arenas, Benoit Crousse. An Overview of 4‐ and 5‐Halo‐1,2,3‐triazoles from Cycloaddition Reactions. European Journal of Organic Chemistry, 2021, 2021 (18), pp.2665 - 2679. ⟨10.1002/ejoc.202100327⟩. ⟨hal-03796522⟩
Ren-Jin Tang, Pascal Retailleau, Thierry Milcent, Benoit Crousse. Direct Amination of Arenes with Azodicarboxylates Catalyzed by Bisulfate Salt/HFIP Association. ACS Omega, 2019, 4 (5), pp.8960-8966. ⟨10.1021/acsomega.9b00781⟩. ⟨hal-02347296⟩
Monika Skibińska, Marcin Kaźmierczak, Thierry Milcent, Tomasz Cytlak, Henryk Koroniak, et al.. Direct Access to Substituted 4-CF3 β-Lactams at the C-3 Position. Frontiers in Chemistry, 2019, 7, pp.526. ⟨10.3389/fchem.2019.00526⟩. ⟨hal-02347612⟩
Ren-Jin Tang, Thierry Milcent, Benoit Crousse. Bisulfate Salt-Catalyzed Friedel–Crafts Benzylation of Arenes with Benzylic Alcohols. Journal of Organic Chemistry, 2018, 83 (22), pp.14001-14009. ⟨10.1021/acs.joc.8b02361⟩. ⟨hal-02347577⟩
Faustine Bizet, Nicolo Tonali, Jean-Louis Soulier, Agostino Oliva, Julia Kaffy, et al.. Towards a general synthesis of di-aza-amino acids containing peptides. New Journal of Chemistry, 2018, 42 (20), pp.17062-17072. ⟨10.1039/c8nj03635g⟩. ⟨hal-02347605⟩
Benoît Crousse, Pascal Retailleau, Thierry Milcent, Sandrine Ongeri, Vadim A. Soloshonok. Synthesis of Trifluoromethylated Pyrrolidine and Piperidine Amino Acids. SYNFACTS, 2018, 14 (10), pp.1015. ⟨10.1055/s-0037-1610969⟩. ⟨hal-02347510⟩
Jing Hao, Thierry Milcent, Pascal Retailleau, Vadim Soloshonok, Sandrine Ongeri, et al.. Asymmetric Synthesis of Cyclic Fluorinated Amino Acids. European Journal of Organic Chemistry, 2018, 2018 (27-28), pp.3688-3692. ⟨10.1002/ejoc.201800255⟩. ⟨hal-02347674⟩
Thierry Milcent, Benoit Crousse. The main and recent syntheses of the N-CF3 motif. Comptes Rendus. Chimie, 2018, 21 (8), pp.771-781. ⟨10.1016/j.crci.2017.09.003⟩. ⟨hal-02347644⟩
Ren-Jin Tang, Thierry Milcent, Benoit Crousse. Hexafluoroisopropanol as a Solvent for Halogenation of (Het)aromatics. SYNFACTS, 2018, 14 (3), pp.0244. ⟨10.1055/s-0037-1609312⟩. ⟨hal-02347456⟩
Ren-Jin Tang, Thierry Milcent, Benoit Crousse. Regioselective Halogenation of Arenes and Heterocycles in Hexafluoroisopropanol. Journal of Organic Chemistry, 2018, 83 (2), pp.930-938. ⟨10.1021/acs.joc.7b02920⟩. ⟨hal-02347571⟩
Ren-Jin Tang, Thierry Milcent, Benoit Crousse. Friedel–Crafts alkylation reaction with fluorinated alcohols as hydrogen-bond donors and solvents. RSC Advances, 2018, 8 (19), pp.10314-10317. ⟨10.1039/c8ra01397g⟩. ⟨hal-02347433⟩
Yaochun Xu, Isabelle Correia, Tap Ha-Duong, Nadjib Kihal, Jean-Louis Soulier, et al.. The use of 4,4,4-trifluorothreonine to stabilize extended peptide structures and mimic β-strands. Beilstein Journal of Organic Chemistry, 2017, 13, pp.2842 - 2853. ⟨10.3762/bjoc.13.276⟩. ⟨hal-01700974⟩
Ren-Jin Tang, Thierry Milcent, Benoit Crousse. Hexafluoro-2-propanol Promotes para -Selective C-H Amination of Free Anilines with Azodicarboxylates. European Journal of Organic Chemistry, 2017, 2017 (32), pp.4753-4757. ⟨10.1002/ejoc.201700794⟩. ⟨hal-02998179⟩
Julia Kaffy, Dimitri Brinet, Jean-Louis Soulier, Isabelle Correia, Nicolo Tonali, et al.. Designed Glycopeptidomimetics Disrupt Protein–Protein Interactions Mediating Amyloid β-Peptide Aggregation and Restore Neuroblastoma Cell Viability. Journal of Medicinal Chemistry, 2016, 59 (5), pp.2025-2040. ⟨10.1021/acs.jmedchem.5b01629⟩. ⟨hal-02467871⟩
Alena Fedotova, Benoît Crousse, Isabelle Chataigner, Jacques Maddaluno, Alexander Yu. Rulev, et al.. Benefits of a Dual Chemical and Physical Activation: Direct aza-Michael Addition of Anilines Promoted by Solvent Effect under High Pressure. Journal of Organic Chemistry, 2015, 80 (20), pp.10375-10379. ⟨10.1021/acs.joc.5b01756⟩. ⟨hal-02019190⟩
Gilles Berger, Luca Fusaro, Michel Luhmer, Arie van Der Lee, Benoît Crousse, et al.. Synthesis of α-CF3 azanorbornene and azetidines by aza Diels–Alder or iodine-mediated cyclizations: application in ROMP and ligand design. Tetrahedron Letters, 2014, 55 (46), pp.6339 - 6342. ⟨10.1016/j.tetlet.2014.09.105⟩. ⟨hal-01687576⟩
Julia Kaffy, Dimitri Brinet, Jean-Louis Soulier, Lucie Khemtémourian, Olivier Lequin, et al.. Structure-activity relationships of sugar-based peptidomimetics as modulators of amyloid β-peptide early oligomerization and fibrillization.. European Journal of Medicinal Chemistry, 2014, 86C, pp.752-758. ⟨10.1016/j.ejmech.2014.09.031⟩. ⟨hal-01067196⟩
Jing Chen, Daniela Vuluga, Benoit Crousse, Julien Legros, Jannick Duchet-Rumeau, et al.. Polyfluorinated mercaptoalcohol as a H-bond modifier of poly(2,3,4,5,6-pentafluorostyrene) (PPFS) enhancing miscibility of hydroxylated-PPFS with various acceptor polymers. Polymer, 2013, 54 (15), pp.3757-3766. ⟨10.1016/j.polymer.2013.05.027⟩. ⟨hal-02326099⟩
Massaba Keita, Rocco de Bona, Mickaël dos Santos, Olivier Lequin, Sandrine Ongeri, et al.. Access to novel amino trifluoromethyl cyclopropane carboxylic acid derivatives. Tetrahedron, 2013, 69 (15), pp.3308-3315. ⟨10.1016/j.tet.2013.02.012⟩. ⟨hal-01366842⟩
Ch Venkateswarlu, Pv Balaji, De Kavita, Benoît Crousse, Bruno Figadère, et al.. Straightforward synthesis of 2-propylquinolines under multicomponent conditions in fluorinated alcohols. Journal of Fluorine Chemistry, 2013, pp.94-98. ⟨10.1016/j.jfluchem.2012.12.006⟩. ⟨hal-01015813⟩
Laure Dufau, Ana Sofia Marques Ressurreicao, Roberto Fanelli, Nadjib Kihal, Anamaria Vidu, et al.. Carbonylhydrazide-Based Molecular Tongs Inhibit Wild-Type and Mutated HIV-1 Protease Dimerization. Journal of Medicinal Chemistry, 2012, 55 (15), pp.6762-6775. ⟨10.1021/jm300181j⟩. ⟨hal-01544073⟩
Daniela Vuluga, Julien Legros, Benoit Crousse, Alexandra M. Z. Slawin, Christian Laurence, et al.. Influence of the Structure of Polyfluorinated Alcohols on Bronsted Acidity/Hydrogen-Bond Donor Ability and Consequences on the Promoter Effect. Journal of Organic Chemistry, 2011, 76 (4), pp.1126-1133. ⟨10.1021/jo1023816⟩. ⟨hal-02143178⟩
Daniela Vuluga, Julien Legros, Benoit Crousse, Danièle Bonnet-Delpon. Fluorous 4- N , N -Dimethylaminopyridine (DMAP) Salts as Simple Recyclable Acylation Catalysts. Chemistry - A European Journal, 2010, 16 (6), pp.1776-1779. ⟨10.1002/chem.200902982⟩. ⟨hal-02326126⟩
Claire Madelaine, Olivier Buriez, Benoit Crousse, Isabelle Florent, Philippe Grellier, et al.. Aminocyclopropanes as precursors of endoperoxides with antimalarial activity. Organic & Biomolecular Chemistry, 2010, 8 (24), pp.5591. ⟨10.1039/c0ob00308e⟩. ⟨mnhn-02047403⟩
Daniela Vuluga, Julien Legros, Benoit Crousse, Danièle Bonnet-Delpon. Facile Access to Fluorinated Aryl and Vinyl Ethers through Copper-Catalysed Reaction of Fluoro Alcohols. European Journal of Organic Chemistry, 2009, 2009 (21), pp.3513-3518. ⟨10.1002/ejoc.200900303⟩. ⟨hal-02326135⟩
Daniela Vuluga, Julien Legros, Benoit Crousse, Danièle Bonnet-Delpon. Synthesis of pyrazoles through catalyst-free cycloaddition of diazo compounds to alkynes. Green Chemistry, 2009, 11 (2), pp.156-159. ⟨10.1039/B812242C⟩. ⟨hal-02326141⟩
Daniela Vuluga, Julien Legros, Benoit Crousse, Danièle Bonnet-Delpon. Solubility switch of gold nanoparticles through hydrogen bond association. Chemical Communications, 2008, 40, pp.4954. ⟨10.1039/b810932j⟩. ⟨hal-02326146⟩
Fabienne Grellepois, Fatima Chorki, Michèle Ourévitch, Sébastien Charneau, Philippe Grellier, et al.. Orally Active Antimalarials: Hydrolytically Stable Derivatives of 10-Trifluoromethyl Anhydrodihydroartemisinin †. Journal of Medicinal Chemistry, 2004, 47 (6), pp.1423-1433. ⟨10.1021/jm030947m⟩. ⟨mnhn-02867479⟩

Chapitres d'ouvrage2 document

Benoit Crousse, Thierry Milcent. Synthesis of NCF3, NCF2H and NCH2CF3 motifs. merging Fluorinated Motifs. Properties, Synthesis and Applications, 2020. ⟨hal-03796648⟩
Danièle Bonnet-Delpon, Jean-Pierre Bégué, Benoit Crousse, Fabienne Grellepois, Constance Chollet, et al.. New 10-Trifluoromethyl Monomers, Dimers, and Chimeras of Artemisinin from a Key Allyl Bromide Precursor. Current fluoroorganic chemistry: new synthetic directions, technologies, materials and biological application, ACS Symposium Series, Vol 949, pp.337-351, 2007, ⟨10.1021/bk-2007-0949.ch020⟩. ⟨mnhn-02867458⟩

Pré-publications, Documents de travail2 document

Sandrine Ongeri, Benoît Crousse. Fluorinated triazolamers: preferential conformations and activities on Islet Amyloid Polypeptide (hIAPP) Aggregation. 2025. ⟨hal-05179626⟩
Yazid Boutahri, Khoubaib Ben Haj Salah, Nicolas Tisserand, Nathalie Lensen, Benoit Crousse, et al.. Difluoroalanine: Synthesis, Incorporation in Peptides, and Hydrophobic Contribution Assessment. 2023. ⟨hal-04249424⟩

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