POMEL

Cảnh Hưng Nguyễn, Catherine Cailleau, Natalie Fournier, Luc Augis, Françoise Mercier-Nomé, et al.. Are hydrophilic deep eutectic solvents a potential vehicle for topical delivery of Amphotericin B against cutaneous leishmaniasis? An investigation of physicochemical properties, tolerability and antileishmanial efficacy. International Journal of Pharmaceutics, 2026, 689, pp.126439. ⟨10.1016/j.ijpharm.2025.126439⟩. ⟨hal-05397306⟩
Thais Santos, Eduardo Lages, Tiago Ricotta, Leandro de Oliveira, Guilherme Ramos, et al.. Long-Circulating Liposomes Codelivering Amphotericin B and Retinoic Acid for Cutaneous Leishmaniasis Treatment. ACS Omega, 2025, 10 (41), pp.48514-48530. ⟨10.1021/acsomega.5c06156⟩. ⟨hal-05302818⟩
Ellen Gonçalves De Oliveira, Juliane Sousa Lanza, Sandrine Cojean, Paulo Otávio L. Moreira, Luiza Guimarães Tunes, et al.. Re-sensitization of antimony-resistant Leishmania by highly potent SbV-porphyrin through the involvement of ERG6-coding gene. Biomedicine and Pharmacotherapy, 2025, 187, pp.118059. ⟨10.1016/j.biopha.2025.118059⟩. ⟨hal-05445980⟩
Mathew Choaji, Ascel Samba-Louaka, Zineb Fechtali-Moute, Willy Aucher, Sébastien Pomel. Encystment and Excystment Processes in Acanthamoeba castellanii: An Emphasis on Cellulose Involvement. Pathogens, 2025, 14, ⟨10.3390/pathogens14030268⟩. ⟨hal-04988818⟩
Mohamed Belemlilga, Hazrina Hazni, Aristide Traore, Indira Dennemont, Sébastien Pomel, et al.. Chemical analysis by molecular networking methods on extracts of Saba senegalensis (A.DC.) Pichon (Apocynaceae) and its anthelmintic activity on Caenorhabditis elegans. Clinical Traditional Medicine and Pharmacology, 2025, 6 (1), pp.200195. ⟨10.1016/j.ctmp.2025.200195⟩. ⟨hal-05149228⟩
Zineb Fechtali-Moute, Sébastien Pomel. Influence of the Age of Free-Living Amoeba Cysts on Their Vertical Distribution in a Water Column. Microorganisms, 2024, 12 (3), pp.474. ⟨10.3390/microorganisms12030474⟩. ⟨hal-05149223⟩
Cynthia Demicheli, Virgínia Vallejos, Juliane Lanza, Guilherme Ramos, Bruno Do Prado, et al.. Supramolecular assemblies from antimony(V) complexes for the treatment of leishmaniasis. Biophysical Reviews, 2023, 15 (4), pp.751-765. ⟨10.1007/s12551-023-01073-6⟩. ⟨hal-05149219⟩
Zineb Fechtali-Moute, Philippe Loiseau, Sébastien Pomel. Stimulation of Acanthamoeba castellanii excystment by enzyme treatment and consequences on trophozoite growth. Frontiers in Cell and Developmental Biology, 2022, 10, ⟨10.3389/fcell.2022.982897⟩. ⟨hal-05149208⟩
Antonio Lipa Castro, Sébastien Pomel, Catherine Cailleau, Natalie Fournier, Indira Dennemont, et al.. Pharmacokinetics, biodistribution, and activity of Amphotericin B-loaded nanocochleates on the Leishmania donovani murine visceral leishmaniasis model. International Journal of Pharmaceutics, 2022, 624, pp.121985. ⟨10.1016/j.ijpharm.2022.121985⟩. ⟨hal-05149201⟩
Juliane Lanza, Virginia Vallejos, Guilherme Ramos, Ana Carolina B. de Oliveira, Cynthia Demicheli, et al.. Nanoassemblies from Amphiphilic Sb Complexes Target Infection Sites in Models of Visceral and Cutaneous Leishmaniases. Pharmaceutics, 2022, 14 (8), pp.1743. ⟨10.3390/pharmaceutics14081743⟩. ⟨hal-05149206⟩
Philippe Loiseau, Kaluvu Balaraman, Gillian Barratt, Sébastien Pomel, Rémy Durand, et al.. The Potential of 2-Substituted Quinolines as Antileishmanial Drug Candidates. Molecules, 2022, 27 (7), pp.2313. ⟨10.3390/molecules27072313⟩. ⟨hal-05149192⟩
Wei Mao, Noureddine Lazar, Herman van Tilbeurgh, Philippe Loiseau, Sébastien Pomel. Minor Impact of A258D Mutation on Biochemical and Enzymatic Properties of Leishmania infantum GDP-Mannose Pyrophosphorylase. Microorganisms, 2022, 10 (2), pp.231. ⟨10.3390/microorganisms10020231⟩. ⟨hal-05149188⟩
Hélène Levaique, Olivier Pamlard, Cécile Apel, Jérôme Bignon, Margaux Arriola, et al.. Alkyl-Resorcinol Derivatives as Inhibitors of GDP-Mannose Pyrophosphorylase with Antileishmanial Activities. Molecules, 2021, 26 (6), pp.1551. ⟨10.3390/molecules26061551⟩. ⟨hal-03354096⟩
Alexandre Taravaud, Zineb Fechtali-Moute, Philippe Loiseau, Sébastien Pomel. Drugs used for the treatment of cerebral and disseminated infections caused by free‐living amoebae. Clinical and Translational Science., 2021, 14 (3), pp.791-805. ⟨10.1111/cts.12955⟩. ⟨hal-05149186⟩
Liwen Feng, Sébastien Pomel, Perle Latre de Late, Alexandre Taravaud, Philippe M Loiseau, et al.. Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections. Molecules, 2020, 25 (21), pp.5075. ⟨10.3390/molecules25215075⟩. ⟨hal-03038691⟩
Philippe Loiseau, Sébastien Pomel, Simon Croft. Chitosan Contribution to Therapeutic and Vaccinal Approaches for the Control of Leishmaniasis. Molecules, 2020, 25 (18), pp.4123. ⟨10.3390/molecules25184123⟩. ⟨hal-05149173⟩
Lília Cabral, Sébastien Pomel, Sandrine Cojean, Patrícia Amado, Philippe Loiseau, et al.. Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani. Molecules, 2020, 25 (3), pp.465. ⟨10.3390/molecules25030465⟩. ⟨hal-05149167⟩
Juliane Lanza, Sébastien Pomel, Philippe Loiseau, Frédéric Frézard. Recent advances in amphotericin B delivery strategies for the treatment of leishmaniases. Expert Opinion on Drug Delivery, 2019, 16 (10), pp.1063-1079. ⟨10.1080/17425247.2019.1659243⟩. ⟨hal-05149158⟩
Sébastien Pomel, Wei Mao, Tâp Ha-Duong, Christian Cavé, Philippe Loiseau. GDP-Mannose Pyrophosphorylase: A Biologically Validated Target for Drug Development Against Leishmaniasis. Frontiers in Cellular and Infection Microbiology, 2019, 9, ⟨10.3389/fcimb.2019.00186⟩. ⟨hal-05149150⟩
Alexandre Taravaud, Myriam Ali, Bernard Lafosse, Valérie Nicolas, Cédric Féliers, et al.. Enrichment of free-living amoebae in biofilms developed at upper water levels in drinking water storage towers: An inter- and intra-seasonal study. Science of the Total Environment, 2018, 633, pp.157-166. ⟨10.1016/j.scitotenv.2018.03.178⟩. ⟨hal-05149138⟩
Elodie Jagu, Sébastien Pomel, Alba Diez-Martinez, Estelle Rascol, Stéphanie Pethe, et al.. Synthesis and antikinetoplastid evaluation of bis(benzyl)spermidine derivatives. European Journal of Medicinal Chemistry, 2018, 150, pp.655-666. ⟨10.1016/j.ejmech.2018.02.087⟩. ⟨hal-05149126⟩
Vasanthan Ravichandran, Nalia Mekarnia, Sébastien Pomel, Sandrine Cojean, Laurent Ferrié, et al.. New Water-Soluble Polymeric Prodrugs of 2-n-propylquinoline: Synthesis and Evaluation of In Vitro and In Vivo Activities Against Leishmania donovani. Regenerative Engineering and Translational Medicine, 2018, 4 (1), pp.11-20. ⟨10.1007/s40883-018-0045-3⟩. ⟨hal-05149115⟩
Pedro Vásquez-Ocmín, Sandrine Cojean, Elsa Rengifo, Soulaf Suyyagh-Albouz, Carlos Amasifuen Guerra, et al.. Antiprotozoal activity of medicinal plants used by Iquitos-Nauta road communities in Loreto (Peru). Journal of Ethnopharmacology, 2018, 210, pp.372-385. ⟨10.1016/j.jep.2017.08.039⟩. ⟨hal-05149102⟩
Alexandre Taravaud, Philippe Loiseau, Sébastien Pomel. In vitro evaluation of antimicrobial agents on Acanthamoeba sp. and evidence of a natural resilience to amphotericin B. International journal for parasitology. Drugs and drug resistance, 2017, 7 (3), pp.328-336. ⟨10.1016/j.ijpddr.2017.09.002⟩. ⟨hal-05149091⟩
Elodie Jagu, Sébastien Pomel, Stéphanie Pethe, Philippe Loiseau, Raphaël Labruère. Polyamine-based analogs and conjugates as antikinetoplastid agents. European Journal of Medicinal Chemistry, 2017, 139, pp.982-1015. ⟨10.1016/j.ejmech.2017.08.014⟩. ⟨hal-05149085⟩
Elodie Jagu, Sébastien Pomel, Alba Diez-Martinez, Florence Ramiandrasoa, R. Luise Krauth-Siegel, et al.. Synthesis and in vitro antikinetoplastid activity of polyamine–hydroxybenzotriazole conjugates. Bioorganic and Medicinal Chemistry, 2017, 25 (1), pp.84-90. ⟨10.1016/j.bmc.2016.10.013⟩. ⟨hal-05149063⟩
Pierre Daligaux, Sébastien Pomel, Karine Leblanc, Philippe Loiseau, Christian Cavé. Simple and efficient synthesis of 5'-aryl-5'-deoxyguanosine analogs by azide-alkyne click reaction and their antileishmanial activities. Molecular Diversity, 2016, 20 (2), pp.507-519. ⟨10.1007/s11030-015-9652-9⟩. ⟨hal-05149047⟩
Pierre Daligaux, Guillaume Bernadat, Linh Tran, Christian Cavé, Philippe Loiseau, et al.. Comparative study of structural models of Leishmania donovani and human GDP-mannose pyrophosphorylases. European Journal of Medicinal Chemistry, 2016, 107, pp.109-118. ⟨10.1016/j.ejmech.2015.10.037⟩. ⟨hal-05149041⟩
Kaluvu Balaraman, Nashira Campos Vieira, Fathi Moussa, Joël Vacus, Sandrine Cojean, et al.. In vitro and in vivo antileishmanial properties of a 2-n-propylquinoline hydroxypropyl β-cyclodextrin formulation and pharmacokinetics via intravenous route. Biomedicine and Pharmacotherapy, 2015, 76, pp.127-133. ⟨10.1016/j.biopha.2015.10.028⟩. ⟨hal-05149031⟩
Galina Lepesheva, Tatiana Hargrove, Girish Rachakonda, Zdzislaw Wawrzak, Sébastien Pomel, et al.. VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis. Journal of Infectious Diseases, 2015, 212 (9), pp.1439-1448. ⟨10.1093/infdis/jiv228⟩. ⟨hal-05149012⟩
Sébastien Pomel, Sandrine Cojean, Philippe Loiseau. Targeting sterol metabolism for the development of antileishmanials. Trends in Parasitology, 2015, 31 (1), pp.5-7. ⟨10.1016/j.pt.2014.11.007⟩. ⟨hal-05148982⟩

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