
Contact
- Nom : Karine Leblanc
- IdHAL : karine-leblanc91
- CV HAL : CV de Karine Leblanc
- ORCID : 0009-0002-9396-0870 ,
Domains
- Chimie18
- Sciences du Vivant [q-bio]7
- Chimie/Chimie thérapeutique4
- Sciences du Vivant [q-bio]/Microbiologie et Parasitologie4
- Chimie/Chimie analytique3
- Chimie/Chimie organique3
- Sciences du Vivant [q-bio]/Biologie cellulaire3
- Sciences du Vivant [q-bio]/Biologie végétale/Botanique2
- Chimie/Catalyse1
- Chimie/Chemo-informatique1
- Chimie/Chimie théorique et/ou physique1
- Physique [physics]/Matière Condensée [cond-mat]1
- Sciences de l'environnement/Biodiversité et Ecologie1
- Sciences du Vivant [q-bio]/Biologie du développement1
- Sciences du Vivant [q-bio]/Biologie végétale/Phytopathologie et phytopharmacie1
- Sciences du Vivant [q-bio]/Immunologie1
- Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC]1
Keywords
ACL ALKALOIDS Absolute configuration Acid-catalyzed rearrangements Alkali metal Alkaloids Alkylamides Amaryllidaceae Anions Annonaceae Anti-infectious diseases Anti-infectious diseases Metabolomics Peruvian amazonia Piper Cordoncillos Chemical structure Mass spectrometry Molecular networking Molecular structure Monomers Natural products Organic compounds Peptides and proteins
- Molecular networking3
- Organic compounds3
- Alkaloids2
- Chemical structure2
- Mass spectrometry2
- Molecular structure2
- Monomers2
- Natural products2
- Peptides and proteins2
- ACL1
- ALKALOIDS1
- Absolute configuration1
- Acid-catalyzed rearrangements1
- Alkali metal1
- Alkylamides1
- Amaryllidaceae1
- Anions1
- Annonaceae1
- Anti-infectious diseases1
- Anti-infectious diseases Metabolomics Peruvian amazonia Piper Cordoncillos1
- Antileishmanial activity1
- Aplysinopsin1
- Aromatic compounds1
- Article1
- Autodock vina1
- Avicennol1
- BINDING1
- Biodereplication1
- Biomimetic synthesis1
- Boron1
- CATALYSIS1
- COMPLEXES1
- Canthinone alkaloids1
- Carbon1
- Cassane1
- Cassane diterpenoid1
- Catalysts1
- Chemical synthesis1
- Circular dichroism spectroscopy1
- Click reaction1
- Complex1
- Cordoncillos1
- Corynanthe pachyceras1
- Crinum scillifolium1
- Crown ether1
- DIMERS1
- Data1
- Dereplication1
- Diterpene1
- Diverse compounds1
- Docking1
- Erythrophleum suaveolens1
- Fabaceae1
- Flavoalkaloids1
- GUANIDINIUM1
- Greenwayodendron suaveolens1
- Guanosine1
- Heme binding1
- Heme-drug adducts1
- Heterosides1
- IQAMDB1
- IR1
- Ilimaquinone1
- In silico data base1
- Inhibition1
- Isolation1
- Leishmania1
- Lithium1
- Mathematical methods1
- MetWork platform1
- Metabolomics1
- Molecular diversity1
- Molecules1
- Monoterpene indole alkaloids1
- NMR1
- Nuclear magnetic resonance spectroscopy1
- Oligomers1
- Organic synthesis1
- Ozonolysis1
- PHOTOCHEMISTRY1
- PHOTOREACTIONS1
- Peptidomimetics1
- Peruvian amazonia1
- Pharmaceuticals1
- Piper1
- Piper coruscans Kunth Piperaceae1
- Plants1
- Plasmodium1
- Plasmodium falciparum1
- Precursors1
- Quinone addition-reaction1
- Quinones1
- Quorum sensing1
- Radical decarboxylation1
- Reaction products1
- Ring-distortion1
- Rubiaceae1
- SELECTIVITY1
- STONY CORAL1
- Scaffolds1
- Self-assembly1
- Sesquiterpene indole alkaloids1
- Sesquiterpene quinones1
- Sponge dactylospongia-elegans1
- Stereochemistry1
- Synthesis1
- Synthetic methods1
- Total synthesis1
- Unified synthesis1
- Vibrio-harveyi1
- Witkop-Winterfeldt1
- Zanthoxylum chiloperone1
Authors
Leblanc Karine26
Beniddir Mehdi14
Poupon Erwan11
Bernadat Guillaume9
Le Pogam Pierre9
Rharrabti Somia7
Gallard Jean-François7
Champy Pierre6
Gallard Jean-François6
Evanno Laurent6
Kouamé Tapé5
Grellier Philippe5
Mouray Elisabeth4
Beniddir Mehdi A.3
Jullian Jean-Christophe3
Okpekon Aboua Timothée3
Skiredj Adam3
Vanheuverzwijn Jérôme3
Zhou Zhiyu3
Turpin Victor3
Fontaine Véronique3
Leblanc K.3
Arias Antonieta Rojas De2
Bony Nicaise2
Cojean Sandrine2
Coulerie P.2
Eydoux C.2
Ferreira Maria Elena2
Figadère B.2
Fournet Alain2
Guillemot J.-C.2
Hnawia E.2
Jagora Adrien2
Kabran Faustin Aka2
Konan Jacques Dibi2
Lachkar David2
Lannang Alain Meli2
Le Pogam Pierre2
Maciuk A.2
Maciuk Alexandre2
Mkounga Pierre2
N'Tamon Amon Diane2
Nkengfack Augustin Ephrem2
Nour M.2
N’tamon Amon Diane2
Poupon Erwan2
Rodrigo Jordi2
Seon-Meniel Blandine2
Genta-Jouve Grégory2
Retailleau Pascal2
El Kalamouni Chaker2
Said-Hassane Charifat2
Joseph Delphine2
Lebouvier N.2
Ahamada Kadiria1
Ahmont Kablan Claude Landry1
Ake Michèle1
Alcover Charlotte Fox1
Any-Grah Sandrine Aka1
Attioua Barthélemy Koffi1
Attioua Koffi Barthélemy1
Batista Ariane S1
Bayle J.-P.1
Bellettini Ismael C1
Beniddir Mehdi A1
Bertani Stéphane1
Blaud Magali1
Bony Nicaise F.1
Boufridi Asmaa1
Canard B.1
Cebrian-Torrejon Gerardo1
Cebrian-Torrejon Gerardo Cebrian1
Cech Nadja1
Chneiweiss Herve1
Colucci-Guyon Emma1
Costa Bernard1
Daligaux Pierre1
Daouda Ballo1
Denis Stephanie1
Denizot Natacha1
Dennemont Indira1
Derrien Benoit1
Desyergne Audrey1
Duchemin Nicolas1
Dufau Laure1
Dumontet Vincent1
Evanno Laurent1
Fanelli Roberto1
Ferron Solenn1
Figadère Bruno1
Fontaine Véronique1
Fouotsa Hugues1
Fox Ramos Alexander1
Gutierrez Sandra Torijano1
Kablan Ahmont Claude Landry1
Kabran Faustin1
Kahn Suzana Assad1
Kihal Nadjib1
Koffi Armand Angely1
Komlaga Gustav1
Lamali Assia1
Le Goff Géraldine1
Lewin G.1
Loiseau Philippe1
Lopes Philippe1
Mai Phuong-Y1
Mansot Justine1
Mbeng Obame Rany1
Meyer Franck1
Miel Corto1
Moppert Xavier1
Muñoz-Durango Katalina1
N'Nang Elvis Otogo1
N'Negué Marie Andrée1
Ndong Judicael Ella1
Numbi Wa Ilunga Evodie1
Obiang Cédric Sima1
Okpekon Timothée1
Oliveira Suellen D S1
Otogo N'Nang Elvis1
Ouazzani Jamal1
Ovono Abessolo Félix1
Pomel Sébastien1
Rault J.1
Reboud-Ravaux Michele1
Ressurreicao Ana Sofia Marques1
Ricopa Cotrina Hivelli1
Roumy Vincent1
Ruiz Mesia Lastenia1
Ruiz Mesia Wilfredo1
Ruiz-Vásquez Liliana1
Seon-Méniel Blandine1
Sissouma Drissa1
Soulier Jean-Louis1
Spelman Kevin1
Séon-Méniel Blandine1
Thirant Cecile1
Vidu Anamaria1
Vásquez-Ocmín Pedro1
van Baelen Anne-Cécile1
Arseniyadis Stellios1
Tintillier Florent1
Pomel Sébastien1
Bonnaffé David1
Guerra Carlos1
Maciuk Alexandre1
Litaudon Marc1
Fouotsa Hugues1
Meyer Franck1
Amin N'Cho Christophe1
Skiredj Adam1
Szwarc Sarah1
Judeinstein P.1
Saulnier Denis1
Milcent Thierry1
Cavé Christian1
Mbeng Obame Rany1
Drège Emmanuelle1
Berdagué P.1
Petek Sylvain1
Gadea Alice1
Vasseur Jean-Jacques1
Herbomel Philippe1
Debitus Cécile1
Crousse Benoit1
Figadere Bruno1
Figadère Bruno1
Vincent Guillaume1
Marti Guillaume1
Guillot Régis1
Castellano Flavia1
Molinier-Frenkel Valerie1
Smietana Michaël1
Duval Romain1
Ongeri Sandrine1
Marteyn Benoit1
Kouklovsky Cyrille1
Lagarde Nathalie1
Vásquez-Ocmín Pedro1
Beniddir Mehdi A1
Derbré Séverine1
Affiliated authors
Journals
- Organic Letters3
- Journal of Natural Products3
- Angewandte Chemie International Edition2
- Phytochemistry2
- Molecules2
- Data in Brief1
- Chemical Communications1
- Chemistry - A European Journal1
- Molecular Diversity1
- Revista Brasileira de Farmacognosia1
- European Journal of Organic Chemistry1
- Fitoterapia1
- Journal of Medicinal Chemistry1
- Planta Medica International Open1
- Records of Natural Products1
- Organic & Biomolecular Chemistry1
- Planta Medica1
- Tetrahedron1
- Chemical Science1
- Nature Chemistry1
- Journal of Organic Chemistry1
- Frontiers in Pharmacology1
Year of production
Institutions
Laboratories
Departments
Research team
29 documents
Journal articles29 document
- Rany Mbeng Obame, Pierre Le Pogam, Karine Leblanc, Somia Rharrabti, Evodie Numbi Wa Ilunga, et al.. Targeted discovery of sesquiterpene indole alkaloids from Greenwayodendron suaveolens. Phytochemistry, 2026, 241, pp.114664. ⟨10.1016/j.phytochem.2025.114664⟩. ⟨hal-05327820⟩
- Benoit Derrien, Karine Leblanc, Laurent Evanno, Emmanuelle Drège. Enantioselective Total Synthesis of the Neurotoxin Caramboxin. Journal of Organic Chemistry, 2024, 89 (9), pp.6489-6493. ⟨10.1021/acs.joc.4c00541⟩. ⟨hal-05114333⟩
- Sarah Szwarc, Adrien Jagora, Séverine Derbré, Karine Leblanc, Somia Rharrabti, et al.. Combination of Machine Learning and Empirical Computation for the Structural Validation of Trirosaline, a Natural Trimeric Monoterpene Indole Alkaloid from Catharanthus roseus. Organic Letters, 2024, 26 (1), pp.274-279. ⟨10.1021/acs.orglett.3c03972⟩. ⟨hal-04460068⟩
- Phuong-Y Mai, Erwan Poupon, Jamal Ouazzani, Rany Mbeng Obame, Philippe Lopes, et al.. Spirobistetrodecamycins A and B: Spontaneous dimeric spiro-fused vinyl cyclobutanes of tetrodecamycin. Tetrahedron, 2023, 149, pp.133712. ⟨10.1016/j.tet.2023.133712⟩. ⟨hal-04403973⟩
- Pedro Vásquez-Ocmín, Sandrine Cojean, Vincent Roumy, Guillaume Marti, Sébastien Pomel, et al.. Deciphering anti-infectious compounds from Peruvian medicinal Cordoncillos extract library through multiplexed assays and chemical profiling. Frontiers in Pharmacology, 2023, 14 (1100542), pp.1100542. ⟨10.3389/fphar.2023.1100542⟩. ⟨hal-00373615⟩
- Pedro Vásquez-Ocmín, Jean-François Gallard, Anne-Cécile van Baelen, Karine Leblanc, Sandrine Cojean, et al.. Biodereplication of Antiplasmodial Extracts: Application of the Amazonian Medicinal Plant Piper coruscans Kunth. Molecules, 2022, 27 (21), pp.7638. ⟨10.3390/molecules27217638⟩. ⟨mnhn-03904753⟩
- Hugues Fouotsa, Pierre Mkounga, Alain Meli Lannang, Jérôme Vanheuverzwijn, Zhiyu Zhou, et al.. Pyrrovobasine, hybrid alkylated pyrraline monoterpene indole alkaloid pseudodimer discovered using a combination of mass spectral and NMR-based machine learning annotations. Organic & Biomolecular Chemistry, 2022, 20 (1), pp.98-105. ⟨10.1039/d1ob01791h⟩. ⟨hal-04082218⟩
- Hugues Fouotsa, Pierre Le Pogam, Pierre Mkounga, Alain Meli Lannang, Guillaume Bernadat, et al.. Voatriafricanines A and B, Trimeric Vobasine-Aspidosperma-Aspidosperma Alkaloids from Voacanga africana. Journal of Natural Products, 2021, 84 (10), pp.2755-2761. ⟨10.1021/acs.jnatprod.1c00812⟩. ⟨hal-04082176⟩
- Tapé Kouamé, Guillaume Bernadat, Victor Turpin, Marc Litaudon, Aboua Timothée Okpekon, et al.. Structure Reassignment of Melonine and Quantum-Chemical Calculations-Based Assessment of Biosynthetic Scenarios Leading to Its Revised and Original Structures. Organic Letters, 2021, 23 (15), pp.5964-5968. ⟨10.1021/acs.orglett.1c02055⟩. ⟨hal-03470103⟩
- Tapé Kouamé, Timothée Okpekon, Nicaise F. Bony, Solenn Ferron, David Bonnaffé, et al.. Anticipate, Target and Characterize: MS²-anticipated C-glycosylflavones from Erythrococca anomala. Planta Medica International Open, 2021, 8 (03), ⟨10.1055/a-1576-4351⟩. ⟨hal-05480446⟩
- Amon Diane N'Tamon, Aboua Timothée Okpekon, Nicaise Bony, Guillaume Bernadat, Jean-François Gallard, et al.. Streamlined targeting of Amaryllidaceae alkaloids from the bulbs of Crinum scillifolium using spectrometric and taxonomically-informed scoring metabolite annotations. Phytochemistry, 2020, 179, pp.112485. ⟨10.1016/j.phytochem.2020.112485⟩. ⟨mnhn-02977175⟩
- Ahmont Claude Landry Kablan, Jacques Dibi Konan, Gustav Komlaga, Faustin Aka Kabran, Ballo Daouda, et al.. Five new cassane diterpenes from the seeds and bark of Erythrophleum suaveolens. Fitoterapia, 2020, 146, pp.104700 -. ⟨10.1016/j.fitote.2020.104700⟩. ⟨hal-03492054⟩
- Victor Turpin, Mehdi Beniddir, Grégory Genta-Jouve, Adam Skiredj, Jean-François Gallard, et al.. In Silico Anticipation of Metabolic Pathways Extended to Organic Chemistry Reactions: A Case Study with Caffeine Alkaline Hydrolysis and The Origin of Camellimidazoles. Chemistry - A European Journal, 2020, 26 (57), pp.12936-12940. ⟨10.1002/chem.202002196⟩. ⟨hal-04082710⟩
- Tapé Kouamé, Aboua Timothée Okpekon, Nicaise Bony, Amon Diane N’tamon, Jean-François Gallard, et al.. Corynanthean-Epicatechin Flavoalkaloids from Corynanthe pachyceras. Molecules, 2020, Natural Products Chemistry, 25 (11), pp.2654. ⟨10.3390/molecules25112654⟩. ⟨mnhn-02867368⟩
- Charlotte Fox Alcover, Guillaume Bernadat, Faustin Kabran, Pierre Le Pogam, Karine Leblanc, et al.. Molecular Networking Reveals Serpentinine-Related Bisindole Alkaloids from Picralima nitida, a Previously Well-Investigated Species. Journal of Natural Products, 2020, 83 (4), pp.1207-1216. ⟨10.1021/acs.jnatprod.9b01247⟩. ⟨hal-04082731⟩
- Emma Colucci-Guyon, Ariane S Batista, Suellen D S Oliveira, Magali Blaud, Ismael C Bellettini, et al.. Ultraspecific live imaging of the dynamics of zebrafish neutrophil granules by a histopermeable fluorogenic benzochalcone probe. Chemical Science, 2019, 10 (12), pp.3654-3670. ⟨10.1039/c8sc05593a⟩. ⟨hal-02359369⟩
- Jacques Dibi Konan, Barthélemy Koffi Attioua, Faustin Aka Kabran, Claude Landry Ahmont Kablan, Armand Angely Koffi, et al.. Spectroscopic data of new cassane diterpenoids from the root bark of Erythrophleum suaveolens. Data in Brief, 2019, 25, pp.104315. ⟨10.1016/j.dib.2019.104315⟩. ⟨hal-05480445⟩
- Nicolas Duchemin, Adam Skiredj, Justine Mansot, Karine Leblanc, Jean-Jacques Vasseur, et al.. DNA-Templated [2+2] Photocycloaddition: A Straightforward Entry into the Aplysinopsin Family of Natural Products. Angewandte Chemie International Edition, 2018, 57 (36), pp.11786-11791. ⟨10.1002/anie.201806357⟩. ⟨hal-02197152⟩
- Laurent Evanno, David Lachkar, Assia Lamali, Asmaa Boufridi, Blandine Seon-Meniel, et al.. A Ring-Distortion Strategy from Marine Natural Product Ilimaquinone Leads to Quorum Sensing Modulators. European Journal of Organic Chemistry, 2018, 2018 (20-21), pp.2486-2497. ⟨10.1002/ejoc.201800047⟩. ⟨hal-02626088⟩
- David Lachkar, Natacha Denizot, Guillaume Bernadat, Kadiria Ahamada, Mehdi Beniddir, et al.. Unified biomimetic assembly of voacalgine A and bipleiophylline via divergent oxidative couplings. Nature Chemistry, 2017, 9 (8), pp.793-798. ⟨10.1038/nchem.2735⟩. ⟨hal-05115363⟩
- Pierre Daligaux, Sébastien Pomel, Karine Leblanc, Philippe Loiseau, Christian Cavé. Simple and efficient synthesis of 5'-aryl-5'-deoxyguanosine analogs by azide-alkyne click reaction and their antileishmanial activities. Molecular Diversity, 2016, 20 (2), pp.507-519. ⟨10.1007/s11030-015-9652-9⟩. ⟨hal-05149047⟩
- Adam Skiredj, Mehdi Beniddir, Delphine Joseph, Karine Leblanc, Guillaume Bernadat, et al.. A Unified Bioinspired “Aplysinopsin Cascade”: Total Synthesis of (±)-Tubastrindole B and Related Biosynthetic Congeners. Organic Letters, 2014, 16 (19), pp.4980-4983. ⟨10.1021/ol502177m⟩. ⟨hal-05114466⟩
- Adam Skiredj, Mehdi Beniddir, Delphine Joseph, Karine Leblanc, Guillaume Bernadat, et al.. Spontaneous Biomimetic Formation of (±)‐Dictazole B under Irradiation with Artificial Sunlight. Angewandte Chemie International Edition, 2014, 53 (25), pp.6419-6424. ⟨10.1002/anie.201403454⟩. ⟨hal-05114474⟩
- P. Coulerie, A. Maciuk, C. Eydoux, K. Leblanc, E. Hnawia, et al.. New inhibitors of the DENV-NS5 RdRp from Carpolepis laurifolia as potential antiviral drugs for dengue treatment. Records of Natural Products, 2014, 8(3). ⟨hal-03333044⟩
- P. Coulerie, M. Nour, A. Maciuk, C. Eydoux, J.-C. Guillemot, et al.. Structure-Activity Relationship Study of Biflavonoids on the Dengue Virus Polymerase DENV-NS5 RdRp. Planta Medica, 2013, 79(14), ⟨10.1055/s-0033-1350672⟩. ⟨hal-03333046⟩
- Laure Dufau, Ana Sofia Marques Ressurreicao, Roberto Fanelli, Nadjib Kihal, Anamaria Vidu, et al.. Carbonylhydrazide-Based Molecular Tongs Inhibit Wild-Type and Mutated HIV-1 Protease Dimerization. Journal of Medicinal Chemistry, 2012, 55 (15), pp.6762-6775. ⟨10.1021/jm300181j⟩. ⟨hal-01544073⟩
- Gerardo Cebrian-Torrejon, Suzana Assad Kahn, Nathalie Lagarde, Flavia Castellano, Karine Leblanc, et al.. Antiproliferative Activity of trans-Avicennol from Zanthoxylum chiloperone var. angustifolium against Human Cancer Stem Cells. Journal of Natural Products, 2012, 75 (2), pp.257-261. ⟨10.1021/np2004165⟩. ⟨hal-01541436⟩
- Gerardo Cebrian Cebrian-Torrejon, Kevin Spelman, Karine Leblanc, Katalina Muñoz-Durango, Sandra Torijano Gutierrez, et al.. The antiplasmodium effects of a traditional South American remedy: Zanthoxylum chiloperone var. angustifolium against chloroquine resistant and chloroquine sensitive strains of Plasmodium falciparum. Revista Brasileira de Farmacognosia, 2011, 21 (4), pp.652-661. ⟨10.1590/S0102-695X2011005000104⟩. ⟨mnhn-02867451⟩
- K. Leblanc, P. Berdagué, J. Rault, J.-P. Bayle, P. Judeinstein. Synthesis and ionic properties of nematic compounds bearing an ether- crown moiety: An NMR approach. Chemical Communications, 2000, 14, pp.1291-1292. ⟨10.1039/b000501k⟩. ⟨hal-04897766⟩




