Production scientifique – FLUOPEPIT
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Two consecutive aza-amino acids in peptides promote stable β-turn formation in water
While peptides have demonstrated increasing interest as drugs, one major current issue is the design of small peptide analogues [...]
Introducing sequential aza-amino acids units induces repeated β-turns and helical conformations in peptides
A major current issue in medicinal chemistry is the design of small peptide analogues resistant to proteolysis and able [...]
Access to novel amino trifluoromethyl cyclopropane carboxylic acid derivatives
Novel regioisomers of trifluoromethylated cyclopropanes have been synthesized by Michael addition and nucleophilic cyclization process. The reaction was carried [...]
Bioorganic and Medicinal Chemistry of Fluorine (Book)
Bioorganic and Medicinal Chemistry of Fluorine (Book) J.-P. Bégué et D. Bonnet-Delpon Edition - June 2008 72.90 Euro 2008. [...]