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Publications

  • 2024
  1. Composition and Conformation of Hetero‐ versus Homo‐Fluorinated Triazolamers Influence their Activity on Islet Amyloid Polypeptide Aggregation; J. Laxio Arenas, J. Lesma, T. Ha-Duong, B. Sahoo, A. Ramamoorthy, N. Tonali, J-L Soulier, F. Halgand, F. Giraud, B. Crousse, J. Kaffy, S. Ongeri.
    Chem. Eur. J. 2024, e202303887.
  2. Synthesis, Reactivity, and Antibacterial Activity of gem-Difluoroalkene, Difluoromethyl, and Trifluoromethyl β-Lactams;Monika Skibinska, Alicja Warowicka, Henryk Koroniak, Tomasz Cytlak, and Benoît Crousse.
    Org. Lett. 2024, 26, 3, 692–696.
  • 2023
  1. Computational design of cyclic peptides to inhibit protein-peptide interactions; Delaunay M., Ha-Duong T.
    Biophys. Chem., 2023, 296: 106987
  2. Understanding passive membrane permeation of peptides: physical models and sampling methods compared; Mazzanti L., Ha-Duong T.
    Int. J. Mol. Sci., 2023, 24: 5021
  3. Introduction of constrained Trp analogs in RW9 modulates structure and partition in membrane models.; Lozada C., Gonzalez S., Agniel R., Hindie M., Manciocchi L., Mazzanti L., Ha-Duong T., Santoro F., Carotenuto A., Ballet S., Lubin-Germain N.
    Bioorg. Chem., 2023, 139:106731.
  4. Difluoroalanine: Synthesis, Incorporation in Peptides, and Hydrophobic Contribution Assessment.; Boutahri Y., Haj Salah Khoubaib B., Tisserand N., Lensen N., Crousse B., Brigaud T.
    Org. Lett., 2023, 25, 37, 6937–6941
  5. Proteolytically Stable Diaza-Peptide Foldamers Mimic Helical Hot-Spots of Protein-Protein Interactions and Act as Natural Chaperones.; Shi C., Kaffy J., Ha-Duong T., Gallard J-F, Pruvost A., Mabondzo A., Ciccone L., Ongeri S., Tonali N.
    J. Med. Chem. 2023, 66, 12005–12017.
  6. New Hybrid Compounds Incorporating Natural Products as Multifunctional Agents against Alzheimer’s Disease.; Ciccone L., Camodeca C., Tonali N., Barlettani L., Rossello A., Fruchart Gaillard C., Kaffy J., Petrarolo G., La Motta C., Nencetti S., Orlandini E.
    Pharmaceutics 2023, 15 (10), 2369.
  7. Insights into the Structural Conformations of the Tau Protein in Different Aggregation Status.; Pinzi L., Bisi N., Sorbi C., Franchini S., Tonali N., Rastelli G.
    Molecules 2023, 28, 4544.
  8. Recent Advances in the Syntheses of N-CF3 Scaffolds up to Their Valorization.; Crousse B.
    Chem. Rec., 2023, e202300011.
  • 2022
  1. Des3PI: a fragment-based approach to design cyclic peptides targeting protein-protein interactions.; Delaunay M., Ha-Duong T.
    J. Comput. Aided. Mol. Des., 2022, 36, 605-621
  2. Two consecutive aza-amino acids in peptides promote stable β-turn formation in water.; Shi C., Correia I., Tonali N., Ongeri S., Lequin O.
    Org. Biomol. Chem., 2022, 20, 8430 - 8437
  3. Direct Access to Fluorinated Sulfonylhydrazides and Study of Their Reactivity in Thiolation Reaction on Indoles.; Cao T., Crousse B.
    Hel. Chim. Acta, 2022, 105, e202100196
  4. Introducing the Chiral Constrained α-Trifluoromethylalanine in Aib Foldamers to Control, Quantify and Assign the Helical Screw-Sense. ; Bodero L., Guitot K., Lensen N., Lequin O., Brigaud T., Ongeri S., Chaume G.
    Chem-A Eur. J., 2022, 28, e202103887
  5. 5-Fluoro-1,2,3-triazole motif in peptides and its electronic properties.; Laxio Arenas J., Retailleau P., Gillet J-M., Ghermani N.-E., Ongeri S., Crousse B.
    Org. Biomol. Chem., 2022, 20, 8410 – 8414.
  6. A one-pot synthesis and X-Ray structural characterization of new highly substituted-allyl carbamates.; Ghrairi S., Retailleau P., Crousse B., Slimi T.
    J. Mol. Struct., 2022, 132548.
  7. Computational Tools and Strategies to Develop Peptide-Based Inhibitors of Protein-Protein Interactions.; Delaunay M. and Ha-Duong T.
    Methods Mol. Biol., 2022, 2405, 205-230.
  • 2021
  1. Simulations of the Upper Critical Solution Temperature Behavior of Poly(ornithine-co-citrulline)s Using MARTINI-Based Coarse-Grained Force Fields.; Molza AE., Gao P., Jakpou J., Nicolas J., Tsapis N., Ha-Duong T.
    J. Chem. Theory Comput., 2021, 17:4499-4511.
  2. β-chlorovinylaldehydes as intermediates in the synthesis of new substituted β–fluoroalkoxyvinyl aldehydes and corresponding alcohols.; Ghrairi S., Essalah K., Crousse B., Barhoumi-Slimi T.
    J. Fluorine Chem., 2021, 248, 109837.
  3. An Overview of 4- and 5-Halo‐1,2,3-triazoles from Cycloaddition Reactions. ; Laxio Arenas J., Crousse B.
    Eur. JOC, 2021, 18, 2665-2679
  4. Supramolecular Organization of Polymer Prodrug Nanoparticles Revealed by Coarse-Grained Simulations.; P. Gao, J. Nicolas and T. Ha-Duong.
    J. Am. Chem. Soc. 2021, 143, 42, 17412–17423.
  5. Synthesis of N-CF3 hydrazines through radical trifluoromethylation of azodicarboxylates.; T. Cao, P. Retailleau, T. Milcent and B. Crousse.
    Chem. Comm., 2021, 57, 10351.
  6. β-Hairpin Peptide Mimics Decrease Human Islet Amyloid Polypeptide (hIAPP) Aggregation.; J. Lesma, F. Bizet, C. Berardet, N. Tonali, S. Pellegrino,
    M. Taverna, L. Khemtemourian, J-L. Soulier, C. van Heijenoort,
    F. Halgand, T. Ha-Duong, J. Kaffy and S. Ongeri.
    Frontiers in Cell and Dev. Biol. 2021, 9, art. 729001.
  7. α-Synuclein: An All-Inclusive Trip Around its Structure, Influencing Factors and Applied Techniques.; N. Bisi, L. Feni, K. Peqini, H. Pérez-Peña, S. Ongeri, S. Pieraccini and S. Pellegrino .
    Frontiers in Chemistry, 2021, 9, art. 666585.
  8. Peptidotriazolamers Inhibit Aβ(1-42) Oligomerization and Cross a Blood-Brain-Barrier Model.; N. Tonali, L. Hericks, D. C. Schröder, O. Kracker, R. Krzemieniecki, J. Kaffy, V. Le Joncour, P. Laakkonen, A. Marion, S. Ongeri, V. I. Dodero, N. Sewald.
    ChemPlusChem, 2021, 86, 6, 840.
  9. Fluorinated Triazole Foldamers: Folded or Extended Conformational Preferences.; J. Laxio Arenas, Y. Xu, T. Milcent, C. Van Heijenoort, F. Giraud, T. Ha-Duong, B. Crousse, S. Ongeri.
    ChemPlusChem, 2021, 86, 2, 241.
  • 2020
  1. Introducing sequential aza-amino acids units induces repeated β-turns and helical conformations in peptides.; N. Tonali, I. Correia, J. Lesma, G. Bernadat, S. Ongeri and O. Lequin.
    Org. Biomol. Chem., 2020, 18, 3452.
  2. Real‐time BODIPY‐binding assay to screen inhibitors of the early oligomerization process of Aβ 1‐42 peptide; N. Tonali, V. I. Dodero, J. Kaffy, L. Hericks, S. Ongeri, N. Sewald.
    ChemBioChem 2020, 21, 1129.
  3. Evidence for different in vitro oligomerization behavior of synthetic hIAPP obtained from different sources; C. Berardet, J. Kaffy, F. Halgand, G. Van der Rest, S. Ongeri, M. Taverna.
    Analytical and Bioanalytical Chemistry 2020, 412, 3103.
  • 2019
  1. Direct Access to Substituted 4-CF3 β-Lactams in C-3 Position.; M. Skibińska, M. Kaźmierczak, T. Milcent, T. Cytlak, H. Koroniak and B. Crousse.
    Frontiers Organic Chemistry, 2019, Vol 7, Article 526. Special issue: Research Topic: Strained Aza-Heterocycles in Synthesis.
  2. MD Simulations Combined with NMR and/or SAXS Data for Characterizing IDP Conformational Ensembles.; Chan-Yao-Chong M., Durand D., Ha-Duong T.
    J. Chem. Inf. Model., 2019, 59, 1743–1758.
  3. Direct Amination of Arenes with Azodicarboxylates Catalyzed by Bisulfate Salt/HFIP Association. ; Tang, R.-J.; Retailleau, P.; Milcent, T.; B. Crousse.
    ACS OMEGA, 2019, 4, 8960-8966.
  4. GDP-Mannose Pyrophosphorylase: A Biologically Validated Target for Drug Development Against Leishmaniasis.; Pomel S., Mao W., Ha-Duong T., Cavé C., Loiseau L.M.
    Frontiers in Cellular and Infection Microbiology 2019, 9, 186–192.
  5. Structural characterization of N-WASP domain V using MD simulations with NMR and SAXS data.; Chan-Yao-Chong M., Deville C., Pinet L., van Heijenoort C., Durand D., Ha-Duong T.
    Biophys. J., 2019, 116, 1216–1227.
  6. Investigation into Early Steps of Actin Recognition by the Intrinsically Disordered N-WASP Domain V.; Chan-Yao-Chong M., Durand D., Ha-Duong T.
    Int. J. Mol. Sci., 2019, 20, 4493–4511.
  7. Peptides and peptidomimetics as inhibitors of protein-protein interactions involving β-sheet secondary structures; J. Laxio-Arenas, J. Kaffy, S. Ongeri,
    Curr. Opin. Chem. Biol. 2019, 52, 157-167.
  • 2018
  1. Bisulfate Salt-Catalyzed Friedel-Crafts Benzylation of Arenes with Benzylic Alcohols.; Tang, R.-J., Milcent T., Crousse B.
    J. Org. Chem., 2018, 83, 14001-14009.
  2. A capillary electrophoresis method to investigate the oligomerization of the human Islet Amyloid Polypeptide involved in Type 2 Diabetes; C. Berardet, J. Kaffy, S. Ongeri, M. Taverna.
    J. Chromatogr. A. 2018, 1578, 83-90.
  3. Conformational ensemble and biological role of the TCTP intrinsically disordered region: Influence of calcium and phosphorylation.; Malard F., Assrir N., Alami M., Messaoudi S., Lescop E., Ha-Duong T.
    J. Mol. Biol. 2018 25;430(11):1621-1639.
  4. Friedel–Crafts alkylation reaction with fluorinated alcohols as hydrogen-bond donors and solvents.; Ren-Jin T., Milcent T., Crousse B.
    RSC Adv., 2018, 8, 10314-10317.
  5. Synthesis of new α-hydroxyphosphonates and α-acetoxyphosphonates; Z. Baccari, M. A. K. Sanhoury, B. Crousse, T. Barhoumi-Slimi.
    Synthetic Communications, 2018, 10, 1199-1205.
  6. Preparation, characterization and solution behavior of alpha-hydroxyphosphonate complexes with tin tetrachloride. ; Z. Baccari, M.A.K. Sanhoury, C. Dejean, B. Crousse, T. Barhoumi-Slimi.
    J. of Molecular Structure, 2018, vol. 1167, 248-254.
  7. The Main and Recent Syntheses of the N-CF3 Motif.; T. Milcent, B. Crousse.
    Comptes rendus chimie, 2018, vol. 21, Issue 8, 771-781. (Revue dans une spéciale issue suite au congrès du fluor français (CFCF2017) à Murol le 15-18 mai 2017).
  8. Towards a general synthesis of di-aza-amino acids containing peptides; F. Bizet, N. Tonali, J.-L. Soulier, A. Oliva, J. Kaffy, B. Crousse, S. Ongeri
    N. J. Chem., 2018, DOI: 10.1039/C8NJ03635G.
  9. Binding modes of a glycopeptidomimetic molecule on Aβ protofibrils: Implication in its inhibition mechanism; L. Tran, J. Kaffy, S. Ongeri; T. Ha-Duong.
    ACS Chem. Neurosci. 2018
  10. Structure-activity Relationships of β-Hairpin Mimics as Modulators of Amyloid β-Peptide Aggregation; N. Tonali, J. Kaffy, J.-L. Soulier, M.L. Gelmi, E. Erba, M. Taverna, C. van Heijenoort, T. Ha-Duong, S. Ongeri
    Eur. J. Med. Chem., 2018, 154, 280-293
  11. Asymmetric synthesis of new cyclic fluorinated amino‐acids;Hao J., Milcent T., Soloshonok V., Ongeri S., Crousse B.
    Eur J. Org. Chem. 2018, 3688–3692
  12. Regioselective Halogenation of Arenes and Heterocycles in Hexafluoroisopropanol; Ren-Jin Tang, Thierry Milcent, and Benoit Crousse; Ren-Jin Tang, Thierry Milcent, and Benoit Crousse
    J. Org. Chem., 2018, 83 (2), pp 930–938
  • 2017
  1. The use of 4,4,4-trifluorothreonine to stabilize extended peptide structures and mimic β-strands; Yaochun Xu, Isabelle Correia, Tap Ha-Duong, Nadjib Kihal, Jean-Louis Soulier, Julia Kaffy, Benoît Crousse, Olivier Lequin and Sandrine Ongeri
    Beilstein J. Org. Chem. 2017, 13, 2842–2853
  2. Hexafluoro-2-propanol Promotes para-Selective C–H Aminationof Free Anilines with Azodicarboxylates; Ren-Jin Tang, Thierry Milcent, and Benoit Crousse
    Eur. J. Org. Chem. 2017, 4753–4757
  3. Synthesis and Characterization of Hairpin Mimics that Modulate the Early Oligomerization and Fibrillization of Amyloid β-Peptide; Leila Vahdati, Julia Kaffy, Dimitri Brinet, Guillaume Bernadat, Isabelle Correia, Silvia Panzeri, Roberto Fanelli, Olivier Lequin, Myriam Taverna, Sandrine Ongeri, and Umberto Piarulli
    Eur. J. Org. Chem. 2017, 2971–2980
  4. N-Difluoromethyl-triazole as a constrained scaffold in peptidomimetics; M. Mamone, R. S. B. Gonçalves, F. Blanchard, G. Bernadat, S. Ongeri, T. Milcent and B. Crousse
    Chem. Commun., 2017, 53, 5024-5027
  5. In vitro monitoring of amyloid β-peptide oligomerization by Electrospray differential mobility analysis: An alternative tool to evaluate Alzheimer’s disease drug candidates ; Dimitri Brinet, François Gaie-Levrel, Vincent Delatour, Julia Kaffy, Sandrine Ongeri, Myriam Taverna
    Talanta 2017, 156, 84-91
  6. Interaction of chemokine receptor CXCR4 in monomeric and dimeric state with its endogenous ligand CXCL12: coarse-grained simulations identify differences; Cutolo, P; Basdevant, N; Bernadat, G; Bachelerie, F; Ha-Duong, T
    J. Biomol. Struct. Dyna. 2017, 35, 399-412
  7. Biochemical analysis of leishmanial and human GDP-Mannose Pyrophosphorylases and selection of inhibitors as new leads; Mao, W; Daligaux, P; Lazar, N; Ha-Duong, T; Cave, C; van Tilbeurgh, H ; Loiseau, PM; Pomel, S
    Scientific Reports 2017, 7, 751
  8. β-Hairpin mimics containing a piperidine–pyrrolidine scaffold modulate the β-amyloid aggregation process preserving the monomer species; S. Pellegrino, N. Tonali, E. Erba, J. Kaffy, M. Taverna, A. Contini, M. Taylor, D. Allsop, M. L. Gelmi and S. Ongeri
    Chem. Sci., 2017, Advance Article
  • 2016
  1. Designed Glycopeptidomimetics Disrupt Protein–Protein Interactions Mediating Amyloid β-Peptide Aggregation and Restore Neuroblastoma Cell Viability;Julia Kaffy, Dimitri Brinet, Jean-Louis Soulier, Isabelle Correia, Nicolo Tonali, Katia Fabiana Fera, Yasmine Iacone, Anaïs R. F. Hoffmann, Lucie Khemtémourian, Benoit Crousse, Mark Taylor, David Allsop, Myriam Taverna, Olivier Lequin, and Sandrine Ongeri
    J. Med. Chem., 2016, 59 (5), pp 2025–2040
  2. Structure of ring-shaped Aβ42 oligomers determined by conformational selection; Linh Tran, Nathalie Basdevant, Chantal Prévost & Tâp Ha-Duong
    Scientific Reports 6, Article number: 21429 (2016)
  3. In vitro monitoring of amyloid β-peptide oligomerization by Electrospray differential mobility analysis: an alternative tool to evaluate Alzheimer’s disease drug candidate Dimitri Brinet, François Gaie-Levrel, Vincent Delatour, Julia Kaffy, Sandrine Ongeri, Myriam Taverna
    Talenta 2016, in press
  4. Insights into the Conformational Ensemble of Human Islet Amyloid Polypeptide from Molecular Simulations; Tran, Linh; Ha-Duong, Tap
    Current Pharmaceutical Design, 2016, 3601-3607
  5. Effect of Post-Translational Amidation on Islet Amyloid Polypeptide Conformational Ensemble: Implications for Its Aggregation Early Steps; Linh Tran and Tâp Ha-Duong
    Int. J. Mol. Sci. 2016, 17(11), 1896
  6. One-pot synthesis of new highly substituted allylic phosphorodiamidates; Leila Bahria, T. Barhoumi-Slimia, R. Malleka, M.A.K. Sanhourya, B. Crousse, M.T. Ben Dhia
    Journal of Fluorine Chemistry, 2016, 189, 96.
  • 2015
  1. Harnessing the Intrinsic Reactivity within the Aplysinopsin Series for the Synthesis of Intricate Dimers: Natural from Start to Finish ; Skiredj A., Beniddir M.A., Joseph D., Bernadat G., Evanno L., Poupon E.
    Synthesis-Stuttgart, 2015, 16, 2367-2376.
  2. IsoCombretaQuinazolines: Potent Cytotoxic Agents with Antitubulin Activity.; Soussi M.A., Provot O., Bernadat G., Bignon J., Desravines D., Dubois J., Brion J.-D., Messaoudi S., Alami M.
    ChemMedChem., 2015, 8, 1392-1402.
  3. Rapid synthesis of 4-arylchromenes from ortho-substituted alkynols: A versatile access to restricted isocombretastatin A-4 analogues as antitumor agents; Renko D., Provot O., Rasolofonjatovo E., Bignon J., Rodrigo J., Dubois J., Brion J.-D., Hamze A., Alami M.
    Eur. J. Med. Chem., 2015, 90, 834-844
  4. Diversity-oriented synthesis of fused thioglycosyl benzo[e][1,4] oxathiepin-5-ones and benzo[f][1,4]thiazepin-5(2H)-ones by a sequence of palladium-catalyzed glycosyl thiol arylation and deprotection-lactonization reactions.; AL-Shuaeeb R.A.A., Galvani G., Bernadat G., Brion J.-D., Alami M., Messaoudi S.
    Org. Biomol. Chem., 2015, 44, 10904-10906
  5. Regio-, Diastereo-, and Enantioselective Nitroso-Diels-Alder Reaction of 1,3-Diene-1-carbamates Catalyzed by Chiral Phosphoric Acids.; Pous J., Courant T., Bernadat G., Iorga B.I., Blanchard F., Masson G.
    J. Am. Chem. Soc., 2015, 37, 11950-11953.
  6. Overlapping binding sites drive allosteric agonism and positive cooperativity in type 4 metabotropic glutamate receptors. ; Rovira X., Malhaire F., Scholler P., Rodrigo J., Gonzalez-Bulnes P., Llebaria A.; Pin J.-P., Giraldo J., Goudet C.
    Faseb Journal, 2015, 1, 116-130
  7. Benefits of a Dual Chemical and Physical Activation: Direct aza-Michael Addition of Anilines Promoted by Solvent Effect under High Pressure. ; Fedotova A., Crousse B., Chataigner I., Maddaluno J., Rulev A.Y., Legros J.
    J. Org. Chem., 2015, 20, 10375-10379
  8. Cetuximab directly inhibits P-glycoprotein function in vitro independently of EGFR binding.; Chu C., Noel-Hudson M.S., Benard J., Ha-Duong T., Allaoui F., Farinotti R., Bonhomme-Faivre L.
    Eur. J. Pharm. Sci., 2015, 76, 18-26
  9. Exploring the Alzheimer amyloid-beta peptide conformational ensemble: A review of molecular dynamics approaches.; Tran L., Ha-Duong T.
    Peptides, 2015, 69, 86-91
  10. Reactivity of carbon dioxide in hydrofluoroethers: a facile access to cyclic carbonates; Marius Mamone, Thierry Milcent and Benoit Crousse
    Chem. Commun., 2015, 51, 12736-12739
  11. Electrophilic Amination of Fluoroalkyl Groups on Azodicarboxylate Derivatives; Marius Mamone, Estelle Morvan, Thierry Milcent, Sandrine Ongeri, and Benoit Crousse
    J. Org. Chem., 2015, 80 (3), pp 1964–1971
  12. Synthesis and conformational studies of a stable peptidomimetic β-hairpin based on a bifunctional diketopiperazine turn inducer; Leila Vahdati, Roberto Fanelli, Guillaume Bernadat, Isabelle Correia, Olivier Lequin, Sandrine Ongeri and Umberto Piarulli
    New J. Chem., 2015,39, 3250-3258
  • 2014
  1. Structure-activity Relationships of Sugar-based peptidomimetics as modulators of amyloid B-peptide early oligomerization and fibrillization; J. Kaffy, D. Brinet, J-L Soulier, L. Khemtémourian, O. Lequin, M. Taverna, B. Crousse, S. Ongeri.
    Eur. J. Med. Chem. 2014, 86, 752-758.
  2. An improved CE method for the In vitro monitoring of the challenging early steps of the Aβ1-42 peptide oligomerization: application to anti-Alzheimer’s drug discovery. D. Brinet, J. Kaffy, F. Oukacine, S. Glumm, S. Ongeri, M. Taverna.
    Electrophoresis, 2014, 35, 23, 3302-3309.
  3. Toward the Total Synthesis of Klaivanolide: Complete Reinterpretation of Its Originally Assigned Structure. Laurent Ferrié, Sabrina Ferhi, Guillaume Bernadat, Bruno Figadère.
    European Journal of Organic Chemistry, 2014, 28, 6183-6189.
  4. Access to Novel Functionalized Trifluoromethyl ß-Lactams By Ring Expansion of Aziridines. S. Descamps, L. Sevaille, S. Ongeri, B. Crousse.
    Org. Biomol. Chem. 2014, 12, 6345-8.
  5. A Unified Bioinspired “Aplysinopsin Cascade”: Total Synthesis of (±)-Tubastrindole B and Related Biosynthetic Congener. Adam Skiredj, Mehdi A. Beniddir, Delphine Joseph, Karine Leblanc, Guillaume Bernadat, Laurent Evanno and Erwan Poupon.
    Organic Letters, 2014, 16 (19), 4980–4983.
  6. Coarse-Grained Models of the Proteins Backbone Conformational Dynamics ; T. Ha-Duong
    Protein Conformational Dynamics, 2014, Ed. by K.L. Han, X. Zhang and M.J. Yang, Springer, Switzerland, pp.157-169.
  7. Influence of GTP/GDP and Magnesium Ion on the Solvated Structure of the Protein FtsZ : A Molecular Dynamics Study. Jamous C., Basdevant N., Ha-Duong T..
    J. Biomol. Struct. Dyn., 2014, 32, 916-927.
  8. Introduction of polar groups on the naphthalene scaffold of molecular tongs inhibiting wild-type and mutated HIV-1 protease dimerization. R. Fanelli, A. S. Ressurreiçao, L. Dufau, J.-L. Soulier, A. Vidu, N. Tonali, G. Bernadat, M. Reboud-Ravaux, S. Ongeri.
    MedChemComm 2014, 5 (6), 719 - 727.
  9. 19F NMR Monitoring of the Eukaryotic 20S Proteasome Chymotrypsin-like Activity: Investigative tool for studying Allosteric Regulation. M. Keita, J. Kaffy, C. Troufflard, E. Morvan, B. Crousse and S. Ongeri.
    Org. Biomol. Chem. 2014, 12, 4576 – 4581.
  10. Spontaneous Biomimetic Formation of (±)-Dictazole B under Irradition with Artificial Sunlight. Skiredj A., Beniddir M. A., Joseph D., Leblanc K., Bernadat G., Evanno L., Poupon E.
    Angew. Chem. Int. Ed. 2014, 53, (25), 6419–6424
  11. Highly Stereoselective aza-Baylis–Hillman Reactions of CF3-Sulfinylimines: Straightforward Access to α-Methylene β-CF3 β-Amino Acids. Thierry Milcent, Jing Hao, Kosuke Kawada, Vadim A. Soloshonok, Sandrine Ongeri, and Benoit Crousse.
    Eur. J. Org. Chem. 2014, 3072–3075.
  12. Discovery of azaisoerianin derivatives as potential antitumors agents. Soussi M. A., Provot O., Bernadat G., Bignon. J., Wdzieczak-Bakala J., Desravines D., Dubois J., Brion. J.-D., Messaoudi S., Alami M.
    Eur. J. Med. Chem. 2014, 78, 178-189.
  • 2013
  1. Straightforward synthesis of 2-propylquinolines under multicomponent conditions in fluorinated alcohols. Venkateswarlu C., Balaji P.V., De K., Crousse B., Figadère B., Legros J.
    J. Fluorine Chem., 2013, 152, 94-98.
  2. Synthesis, biological evaluation, and structure-activity relationships of tri- and tetrasubstituted olefins related to isocombretastatin A-4 as new tubulin inhibitors. Aziz J., Brachet É., Hamze A., Peyrat J.-F., Bernadat G., Morvan E., Bignon J., Wdzieczak-Bakala J., Desravines D., Dubois J., Tueni M., Yassine A., Brion J.-D., Alami M.
    Org. Biomol. Chem. 2013, 11, 430-442.
  3. α- and β-hydrazino acid-based pseudopeptides inhibit the chymotrypsin-like activity of the eukaryotic 20S proteasome Andrea Bordessa, Massaba Keita, Xavier Maréchal, Lucia Formicola, Nathalie Lagarde , Jordi Rodrigo, Guillaume Bernadat, Cyril Bauvais, Jean-Louis Soulier , Laure Dufau, Thierry Milcent , Benoit Crousse ,Michèle Reboud-Ravaux , Sandrine Ongeri.
    European Journal of Medicinal Chemistry, 70, 2013, 505-524
  4. Semisynthesis of (+)- and (-)-goniomitine from (-)- and (+)-vincadifformine. Lewin G., Bernadat G., Aubert G., Cresteil T.
    Tetrahedron, 2013, 69, 1622-1627.
  5. Toward the strengthening of H-bond donation of hydroxylated poly(2,3,4,5,6-pentafluorostyrene) prepared by thiol-para-fluoro coupling thanks to polyfluorinated mercaptoalcohol
    J. Chena, D. Vuluga, J. Legros, B. Crousse, J. Duchet-Rumeau, A. Charlot, D. Portinha.
    Polymer 2013 (54) 3757.
  6. Straightforward synthesis of 2-propylquinolines under multicomponent conditions in fluorinated alcohols. Ch. Venkateswarlu, P.V. Balaji, Kavita De, Benoit Crousse, Bruno Figadère, Julien Legros J.
    Fluorine Chem. 2013 (152) 94.
  7. Access to novel amino trifluoromethyl cyclopropane carboxylic acid derivatives. Massaba Keita, Rocco De Bona, Mickael Dos Santos, Olivier Lequin, Sandrine Ongeri, Thierry Milcent, Benoit Crousse.
    Tetrahedron 2013 69 (15), 3308.
  8. Modelling protein-protein recognition in solution using the coarse-grained force-field SCORPION. Basdevant N., Borgis D., Ha-Duong T.
    J. Chem. Theory Comput., 2013, 9, 803-813.
  9. Toward the strengthening of H-bond donation of hydroxylated poly(2,3,4,5,6-pentafluorostyrene) prepared by thiol-para-fluoro coupling thanks to polyfluorinated mercaptoalcohol. Chena J., Vuluga D., Legros J., Crousse B., Duchet-Rumeau J., Charlot A., Portinha D.
    Polymer, 2013, 54, 3757-3766.
  10. A One Pot Synthesis of 3-CF3-2-Isoxazolines From The Trifluoromethyl Aldoxime. Schroeder Borges Goncalves R., Dos Santos M., Bernadat B., Bonnet-Delpon D., Crousse B.
    Beilstein J. Org. Chem., 2013, 9, 2387-2394. Special issue on fluorine chemistry, editor David O’Hagan.
  11. Non covalent proteasome inhibitors
    Julia Kaffy, Guillaume Bernadat, Sandrine Ongeri.
    Current Pharmaceutical Design 2013, 19, 4115-4130.
  • 2012
  1. Synthesis of Fluorinated N-Aminoaziridines: Access to New CF3-Peptidomimetics B. Schweitzer-Chaput, M. Keita, T. Milcent, S. Ongeri, B. Crousse.
    Tetrahedron 2012, 68 (35), 7028.
  2. Synthesis and evaluation of fluorinated analogues of monoamine reuptake inhibitors. Christine Philippe, Julia Kaffy, Thierry Milcent, Daniele Bonnet-Delpon.
    J. Fluorine Chem. 2012 134, 136-145.
  3. Carbonylhydrazide-based molecular tongs inhibit wild-type and mutated HIV-1 protease dimerization. Dufau, Laure; Marques Ressurreição, Ana Sofia; Fanelli, Roberto; Kihal, Nadjib; Vidu, Anamaria; Milcent, Thierry; Soulier, Jean-Louis; Rodrigo De Losada, Jordi; Desvergne, Audrey; Leblanc, Karine; Guillaume Bernadat; Crousse, Benoit; Reboud-Ravaux, Michèle; Ongeri, Sandrine.
    J. Med. Chem. 2012 55 (15) 6762-6775.
  4. Self-assembly between 1,4-diazabicyclo[2.2.2]octane and bis(hexafluoroalcohols): solid/liquid phase switching for catalyst recycling. Julien Legros, Danièle Bonnet-Delpon, Benoit Crousse and Alexandra M. Z. Slawin
    Catalysis Science & Technology 2012, 2 (5), 934 - 936.
  5. Platinum-Catalyzed Substitution of Allylic Fluorides. Elena Benedetto, Massaba Keita, Matthew Tredwell, Charlotte Hollingworth, John M. Brown and Véronique Gouverneur.
    Organometallics, 2012, 31 (4), 1408-1416.
  6. The Fluorous Effect in Biomolecular Applications: A Tutorial Review
    Milani Roberto, Massimo Cometti, Benoit Crousse, Giuseppe Resnati, Pierangelo Metrangolo.
    Chem. Soc. Rev. 2012, 41, 31-42.
  • 2011
  1. Transition metal-catalyzed cyclopropanation of alkenes in fluorinated alcohols. Azzouzi-Zriba, Kaouther; Bonnet-Delpon, Daniele; Crousse, Benoit
    J. Fluorine Chemistry 2011, 132 (10), 811-814.
  2. Sugar-based peptidomimetics inhibit amyloid beta-peptide aggregation. Dorgeret, Bertrand; Khemtemourian, Lucie; Correia, Isabelle; et al.
    Eur. J. Med. Chem. 2011, 46 (12), 5959-5969.
  3. Fluorous tagging of DABCO through halogen bonding: recyclable catalyst for the Morita-Baylis-Hillman reaction. Dordonne, Sophie; Crousse, Benoit; Bonnet-Delpon, Daniele
    Chem. Com. 2011, 47, 5855-5857.
  4. Nonmetal Catalyzed Insertion Reactions of Diazocarbonyls to Acid Derivatives in Fluorinated Alcohols. Dumitrescu, Lidia; Azzouzi-Zriba, Kaouther; Bonnet-Delpon, Daniele
    Org. Lett. 2011, 13 (4), 692-695.
  5. Influence of the Structure of Polyfluorinated Alcohols on Bronsted Acidity/Hydrogen-Bond Donor Ability and Consequences on the Promoter Effect. Vuluga, Daniela; Legros, Julien; Crousse, Benoit
    J. Org. Chem. 2011, 76 (4), 1126-1133.
  6. Synthesis of substituted 8-aminoquinolines and phenanthrolines through a Povarov approach. De, Kavita; Legros, Julien; Crousse, Benoit
    Org. & Biomol. Chem. 2011, 9 (2), 347-350.
  • 2010
  1. Toward the First Nonpeptidic Molecular Tong Inhibitor of Wild-Type and Mutated HIV-1 Protease Dimerization. Vidu, Anamaria; Dufau, Laure; Bannwarth, Ludovic; et al.
    ChemMedChem 2010, 5 (11), 1899-1906.
  2. Aminocyclopropanes as precursors of endoperoxides with antimalarial activity. Madelaine, Claire; Buriez, Olivier; Crousse, Benoit
    Organic & Biomolecular Chemistry 2010, 8 (24), 5591-5601.
  3. Synthesis and cytotoxic activity of fluorinated analogues of goniothalamus lactones. Impact of fluorine on oxidative processes.
    Dumitrescu, Lidia; Doan Thi Mai Huong; Nguyen Van Hung; et al.
    Eur. J. of Med. Chem. 2010, 45 (7), 3213-3218
  4. Trifluoromethyl nitrones: from fluoral to optically active hydroxylamines. Milcent, Thierry; Hinks, Nathan; Bonnet-Delpon, Daniele ; Crousse Benoit
    Organic & Biomolecular Chemistry 2010, 8 (13), 3025-3030.
  • 2009
  1. Fluorous 4-N,N-Dimethylaminopyridine (DMAP) Salts as Simple Recyclable Acylation Catalysts. Vuluga, Daniela; Legros, Julien; Crousse, Benoit; et al.
    Chemistry - Eur. J. 2009, 16 (6), 1776-1779.
  2. Cyclic RGD-Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds as New Potent Integrin Ligands. da Ressurreicao, Ana Sofia M.; Vidu, Anamaria; Civera, Monica; et al.
    Chem – Eur. J. 2009, 15 (45), 12184-12188.
  3. Synthesis of New Trifluoromethylated Hydroxyethylamine-Based Scaffolds. Philippe, Christine; Milcent, Thierry; Tam, Nguyen Thi Ngoc; et al.
    Eur. J. Org. 2009, 30, 5215-5223.
  4. Solvent-Promoted and -Controlled Aza-Michael Reaction with Aromatic Amines. De, Kavita; Legros, Julien; Crousse, Benoit; et al.
    J. Org. Chem. 2009, 74, (16), 6260-6265.
  5. Facile Access to Fluorinated Aryl and Vinyl Ethers through Copper-Catalysed Reaction of Fluoro Alcohols. Vuluga, Daniela; Legros, Julien; Crousse, Benoit; et al.
    Eur. J. Org. 2009, 21, 3513-3518
  6. Non Lewis acid catalysed epoxide ring opening with amino acid esters. Philippe, Christine; Milcent, Thierry; Crousse, Benoit; et al.
    Org. Biomol. Chem. 2009, 7 (10), 2026-2028.
  7. Novel fluorinated pseudopeptides as proteasome inhibitors. Formicola L., Maréchal X., Basse N., Bouvier-Durand M., Bonnet-Delpon D., Milcent T., Reboud-Ravaux M., Ongeri S.
    Bioorg Med Chem Lett. 2009, 19(1), 83-86.
  • 2008
  1. Improved Ritter reaction with CF3-containing oxirane for an access to central units of protease inhibitors. Dos Santos, Mickael; Crousse, Benoit; Bonnet-Delpon, Daniele
    Tetrahedron Lett. 2008, 50 (8), 857-859.
  2. Synthesis of pyrazoles through catalyst-free cycloaddition of diazo compounds to alkynes. Vuluga, Daniela; Legros, Julien; Crousse, Benoit; et al.
    Green Chem. 2008, 11 (2), 156-159.
  3. Synthesis of 2,3-unsaturated glycosides via metal-free Ferrier reaction. De, Kavita; Legros, Julien; Crousse, Benoit; et al.
    Tetrahedron 2008, 64 (46), 10497-10500.
  4. Solubility switch of gold nanoparticles through hydrogen bond association. Vuluga, Daniela; Legros, Julien; Crousse, Benoit; et al.
    Chem. Com. 2008, 40, 4954-4955.
  5. Fluorous analogues of DMAP (F-DMAP): Reusable organocatalysts for acylation reaction. Legros, Julien; Crousse, Benoit; Bonnet-Delpon, Daniele
    J. Fluorine Chem. 2008, 129 (10), 974-977.
  6. In vitro antileishmanial activity of fluoro-artemisinin derivatives against Leishmania donovani. Chollet, Constance; Crousse, Benoit; Bories, Christian; et al.
    Biomedicine & Pharmacotherapy 2008, 62 (7), 462-465.
  7. Synthesis of new triazole-based trifluoromethyl scaffolds.
    Martinelli, Michela; Milcent, Thierry; Ongeri, Sandrine; et al.
    Beil. J. Org. Chem. 2008, 4, art. n° 19.
  8. Barbier Conditions for Reformatsky and Alkylation Reactions on Trifluoromethyl Aldimines. Mickael Dos Santos, Benoit Crousse, Danièle Bonnet-Delpon
    Synlett 2008, 3, 399-401.
  9. Synthesis and conformational studies of pseudopeptides containing an unsymmetrical triazine scaffold. Bourguet, Erika; Correia, Isabelle; Dorgeret, Bertrand; et al.
    J. Pept. Science 2008, 14 (5), 596-609.