ONGERI Sandrine

 Professeur

BIOCIS UMR 8076, Université Paris Saclay, CNRS
Team : FLUOPEPIT "Molécules fluorées et peptides d’intérêt thérapeutique"

 Education/Career

• Since 2011 Full Professor in Medicinal Chemistry - BioCIS UMR 8076, Faculty of Pharmacy, Univ. Paris Saclay (ex Univ. Paris Sud)
• 2001-2011 Associate Professor in Medicinal Chemistry - BioCIS UMR 8076, Faculty of Pharmacy, Univ. Paris Sud.
• 1999/2001 Post-Doctoral researcher. Univ Milan (Italy). P^r. C. Gennari. European Grant
• 1995-1999 PhD in Organic Chemistry, Univ. Paris Descartes. Pr. H-P Husson
• 1995/1996 Dyson-Perrins Laboratory, Oxford (UK). P^r. Sir J. E. Baldwin
• 1994/1995 Master Degree in Organic Chemistry Univ. Paris 5.
  One year Research training in Pharmaceutical Company (SERVIER Laboratories).
• 1989-1995 Pharmacy Degree, Faculty of Pharmacy - Univ. Paris 5

 Actual Area of Research

• PEPTIDOMIMETICS INHIBITORS OF PROTEIN/PROTEIN INTERACTIONS INVOLVING ß-SHEETS
  Amyloid proteins aggregation inhibition. ß amyloide peptide, Synuclein, protein tau : Interest in Neurodegenerative diseases. IAPP : interest in type II Diabetes.
  Design of peptidomimetic aggregation inhibitors, synthesis, biophysicochemical evaluation (NMR, Fluorescence, EC, CD, SPR, TEM, IMS-MS, ¹⁹F NMR …), molecular modelling.
• FLUORINATED AMINO ACIDS and PEPTIDES, METHODOLOGY OF SYNTHESIS : trifluoromethylated beta-aminoacides, acyclic, cyclopropanes, aminoaziridines, triazoles…

 Various Activities

• Since 2010 Co-DIRECTION (with D^r. B. Crousse) of the team FLUOPEPIT OF BIOCIS. https://www.biocis.universite-paris-saclay.fr/?-Molecules-fluorees-et-peptides-d-&lang=en. 2 Full Prof, 1 DR CNRS, 3 MCU, 1 IE, PhDs (5-10), Masters (2-3).
• Since 2015 Deputy director of the Doctoral school “Therapeutic innovation” ED569. 300 PhD students. Organization of their multidisciplinary training (scientific and transferable skills). Recruitment management. Conflict management between PhD students and their supervisor. In charge of the International relations and programmes.
• National Academic Collaborations (UMR 8612/UPSaclay, UMR 7203/Sorbonne Univ., LCP/UPSaclay…)
• International Academic Collaborations (Germany, Italy, Israel, Spain, Switzerland, USA)
• National, European and international funding, in particular in HORIZON 2020 programme.
  Partner of ITN "TubInTrain" : https://www.tubintrain.eu/ (2019-2023)
  Partner of FETOPEN "NoPest" : https://www.h2020nopest.org/ (2019-2024) https://eugloh-network.pageflow.io/no-pest
• Industrial collaborations

 Teaching Activities

Medicinal Chemistry : Students in Pharmacy, in M1 and M2 Master in Pharmaceutical Sciences, in L3 Biology-Chemistry (Faculty of Pharmacy and UFR Orsay)
Peptide Chemistry : M1 Master Students in Chemistry (UFR Orsay)

Publications de Sandrine ONGERI - Mars 2024 - 279.7 kio